Neurocrine Biosciences, Inc.

Neurocrine Biosciences, Inc.

NBIXยทNASDAQ

$165.11

+6.6%
HealthcareBiotechnology

Neurocrine Biosciences, Inc. discovers, develops, and markets pharmaceuticals for neurological, endocrine, and psychiatric disorders. The company's portfolio includes treatments for tardive dyskinesia, Parkinson's disease, endometriosis, and uterine fibroids, as well as clinical programs in various therapeutic areas. Its lead asset is INGREZZA, a VMAT2 inhibitor for the treatment of tardive dyskinesia. The company's commercial products include ONGENTYS, a catechol-O-methyltransferase inhibitor used as an adjunct therapy to levodopa/DOPA decarboxylase inhibitors for patients with Parkinson's disease; ORILISSA for the management of moderate to severe endometriosis pain in women; and ORIAHNN, a non-surgical oral medication option for the management of heavy menstrual bleeding associated with uterine fibroids in pre-menopausal women. Its product candidates in clinical development include NBI-921352 for treating pediatric patients, as well as adult focal epilepsy indications; and NBI-827104 to treat rare pediatric epilepsy and essential tremor. The company's products in clinical development also comprise NBI-1065845 for the treatment of major depressive disorder; NBI-1065846 for treating anhedonia in major depressive disorder; and NBI-118568 for the treatment of schizophrenia. It has license and collaboration agreements with Heptares Therapeutics Limited; Takeda Pharmaceutical Company Limited; Idorsia Pharmaceuticals Ltd; Xenon Pharmaceuticals Inc.; Voyager Therapeutics, Inc.; BIAL Portela & Ca, S.A.; Mitsubishi Tanabe Pharma Corporation; and AbbVie Inc. Neurocrine Biosciences, Inc. was incorporated in 1992 and is headquartered in San Diego, California.

At a Glance

Live Snapshot
Market Cap$16.60B
EPS4.8100
P/E Ratio34.33
Earnings Date07/29/2026
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Neurocrine Biosciences, Inc. Street Expectations Map

NBIX ยท NASDAQ

Wall Street analysts project that NBIX stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 186.43, with estimates ranging from a low of 140.00 to a high of 230.00.

Lowest Target
140.00
-15.21%
Consensus Target
186.43
12.91%
Highest Target
230.00
39.30%

The consensus 1-year price target stands at 186.43, with estimates ranging from a low of 140.00 to a high of 230.00.

Analyst Consensus Analysis

Upside Potential

+12.9%

Moderate upside. Analysts expect positive returns but with limited margin of safety. Consider entry timing.

Analyst Agreement

48.3% spread

Mixed analyst views. Wide target range suggests differing opinions on key value drivers, growth prospects, or risk factors.

Risk-Reward Profile

2.58x

Favorable risk-reward. Potential upside significantly exceeds downside risk, offering asymmetric return profile attractive for risk-tolerant investors.

Analyst Conviction

Moderate

Neutral sentiment. Fair value pricing with moderate agreement suggests wait-and-see approach or catalyst-driven opportunity.

Market Sentiment Insight

Asymmetric upside: Strong return potential with favorable risk-reward profile. The limited downside relative to upside makes this an attractive risk-adjusted opportunity for growth-oriented portfolios.

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Neurocrine Biosciences, Inc. Forward Estimates of Revenue

NBIX ยท NASDAQ
Latest Revenue
2.86B
FY 2025
Avg Estimate
3.39B
FY 2026
Estimate Range
3.20B - 3.57B
Analyst Spread

Forward Growth Analysis

Projected Growth+18.3%

Solid growth trajectory indicates healthy business performance and competitive positioning.

Analyst Coverage19 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread11%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Well-supported growth expectations: Strong analyst coverage combined with positive growth projections provides confidence in forward outlook.

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Neurocrine Biosciences, Inc. Forward Estimates of Net Income

NBIX ยท NASDAQ
Latest Net Income
478.60M
FY 2025
Avg Estimate
727.57M
FY 2026
Estimate Range
656.32M - 880.06M
Analyst Spread

Forward Growth Analysis

Projected Growth+52.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage19 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread31%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Well-supported growth expectations: Strong analyst coverage combined with positive growth projections provides confidence in forward outlook.

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Neurocrine Biosciences, Inc. Forward Estimates of EPS

NBIX ยท NASDAQ
Latest EPS
4.81
FY 2025
Avg Estimate
$7.08
FY 2026
Estimate Range
$6.33 - $8.49
Analyst Spread

Forward Growth Analysis

Projected Growth+47.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage13 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread30%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Neurocrine Biosciences, Inc. Forward Estimates of EBIT

NBIX ยท NASDAQ
Latest EBIT
636.50M
FY 2025
Avg Estimate
597.27M
FY 2026
Estimate Range
565.18M - 629.36M
Analyst Spread

Forward Growth Analysis

Projected Growth-6.2%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage19 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread11%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Neurocrine Biosciences, Inc. Forward Estimates of EBITDA

NBIX ยท NASDAQ
Latest EBITDA
666.60M
FY 2025
Avg Estimate
631.88M
FY 2026
Estimate Range
597.92M - 665.83M
Analyst Spread

Forward Growth Analysis

Projected Growth-5.2%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage19 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread11%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Neurocrine Biosciences, Inc. Forward Estimates of SG&A Expense

NBIX ยท NASDAQ
Latest SG&A Expense
1.16B
FY 2025
Avg Estimate
1.58B
FY 2026
Estimate Range
1.49B - 1.66B
Analyst Spread

Forward Growth Analysis

Projected Growth+36.6%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage19 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread11%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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Neurocrine Biosciences, Inc. Insider Positioning

NBIX ยท NASDAQ

During the last 12 months, insiders have sold $83.53M worth of NBIX shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

292.0K

45.22M

Net Activity

-45.2M

-$45.22M

3-6 Months

Bought

0

0.00

Sold

45.2K

6.23M

Net Activity

-6.2M

-$6.23M

6-9 Months

Bought

0

0.00

Sold

54.3K

8.12M

Net Activity

-8.1M

-$8.12M

9-12 Months

Bought

0

0.00

Sold

187.0K

23.96M

Net Activity

-24.0M

-$23.96M

Top Buyers

No buying activity

Top Sellers

1
GKC

Gorman Kevin Charles

Director

351.4K sharesโ€ข2 transactions

$51.27M

2
OJ

Onyia Jude

Officer: Chief Scientific Officer

102.2K sharesโ€ข4 transactions

$13.93M

3
GK

Gano Kyle

Director, Officer: Chief Executive Officer

34.9K sharesโ€ข2 transactions

$4.63M

4
RWH

Rastetter William H

Director

18.0K sharesโ€ข1 transactions

$2.73M

5
PRF

Pops Richard F

Director

15.0K sharesโ€ข1 transactions

$2.36M

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $83.53M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$45.22M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.