Metsera, Inc.

Metsera, Inc.

MTSR·NASDAQ

$70.50

+0.0000%
HealthcareBiotechnology

Metsera, Inc., a clinical-stage biotechnology company, develops injectable and oral nutrient stimulated hormone analog peptides to treat obesity, overweight, and related diseases. It develops MET-097i and MET-233i for the treatment of obesity and overweight; MET-233i/MET-097i; and MET-002, MET-224o, MET-067i, and MET-034i to treat disorders, such as diabetes and obesity. The company was incorporated in 2022 and is headquartered in New York, New York.

At a Glance

Live Snapshot
Market Cap$7.43B
EPS-2.0300
P/E Ratio-34.73
Earnings Date03/25/2026
mtsr

Metsera, Inc. Street Expectations Map

MTSR · NASDAQ

Wall Street analysts project that MTSR stock may decline over the coming 12 months. The consensus 1-year price target stands at 55.50, with estimates ranging from a low of 54.00 to a high of 57.00.

Lowest Target
54.00
-23.40%
Consensus Target
55.50
-21.28%
Highest Target
57.00
-19.15%

The consensus 1-year price target stands at 55.50, with estimates ranging from a low of 54.00 to a high of 57.00.

Analyst Consensus Analysis

Upside Potential

-21.3%

Significant downside risk. Stock trading well above analyst consensus suggests elevated valuation concerns and potential correction.

Analyst Agreement

5.4% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Risk-Reward Profile

0.82x

Unfavorable risk-reward. Downside risk exceeds upside potential. Consider defensive positioning or alternative opportunities.

Analyst Conviction

Low

Bearish or uncertain outlook. Limited upside or poor consensus suggests challenges ahead or fundamental concerns.

Market Sentiment Insight

Consensus overvaluation: Analysts agree the stock is richly valued with limited upside. Consider booking profits or defensive positioning unless you have contrarian conviction in unrecognized catalysts.

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Metsera, Inc. Forward Estimates of Revenue

MTSR · NASDAQ
Latest Revenue
0.00
FY 2024
Avg Estimate
0.00
FY 2025
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

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Metsera, Inc. Forward Estimates of Net Income

MTSR · NASDAQ
Latest Net Income
-209.13M
FY 2024
Avg Estimate
-271.00M
FY 2025
Estimate Range
-356.63M - -215.21M
Analyst Spread

Forward Growth Analysis

Projected Growth-29.6%

Significant contraction projected—major business challenges or industry disruption likely.

Estimate Spread52%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertainty—exercise caution.

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Metsera, Inc. Forward Estimates of EPS

MTSR · NASDAQ
Latest EPS
-2.03
FY 2024
Avg Estimate
$-2.77
FY 2025
Estimate Range
$-3.46 - $-2.09
Analyst Spread

Forward Growth Analysis

Projected Growth-36.7%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread49%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertainty—exercise caution.

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Metsera, Inc. Forward Estimates of EBIT

MTSR · NASDAQ
Latest EBIT
-218.24M
FY 2024
Avg Estimate
0.00
FY 2025
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Metsera, Inc. Forward Estimates of EBITDA

MTSR · NASDAQ
Latest EBITDA
-218.23M
FY 2024
Avg Estimate
0.00
FY 2025
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Metsera, Inc. Forward Estimates of SG&A Expense

MTSR · NASDAQ
Latest SG&A Expense
26.80M
FY 2024
Avg Estimate
0.00
FY 2025
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth-100.0%

Significant contraction projected—major business challenges or industry disruption likely.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

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Metsera, Inc. Insider Positioning

MTSR · NASDAQ

During the last 12 months, insiders have sold $21K worth of MTSR shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

193

11.82K

Net Activity

-12K

-$12K

9-12 Months

Bought

0

0.00

Sold

268

9.65K

Net Activity

-10K

-$10K

Top Buyers

No buying activity

Top Sellers

1
FL

Fmr Llc

10 Percent Owner, Other: See Remark 1

461 shares2 transactions

$21K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $21K net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Insider Participation

High Selling

1 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.