Mineralys Therapeutics, Inc.

Mineralys Therapeutics, Inc.

MLYSยทNASDAQ

$25.06

-19%
HealthcareBiotechnology

Mineralys Therapeutics, Inc., a clinical-stage biopharmaceutical company that develops therapies for the treatment of hypertension and associated cardiovascular diseases. It clinical-stage product candidate is lorundrostat, a proprietary, orally administered, highly selective aldosterone synthase inhibitor for the treatment of patients with uncontrolled or resistant hypertension. The company was incorporated in 2019 and is headquartered in Radnor, Pennsylvania.

At a Glance

Live Snapshot
Market Cap$1.66B
EPS-2.2900
P/E Ratio-10.94
Earnings Date08/11/2026

Intrinsic Alpha Methodology

Thesis Lenses

Signal ยท Driver ยท Risk

Signal

Medium confidence

Valuation multiple is compressed (P/E -10.9).

Valuation inputs: P/E -10.9, earnings yield N/A, momentum -19.4%.

If multiples stay elevated while momentum fades, downside repricing risk rises.

Driver

High confidence

Return profile is soft (ROE -23.9%, ROIC -26.4%).

Profitability stack: net margin 0.0%, ROE -23.9%, ROIC -26.4%.

Quality deterioration often appears in margins before it shows up in headline EPS.

Risk

High confidence

Downside profile is elevated and scenario stress-testing is essential.

Risk factors: liabilities/assets +2.3%, momentum -19.4%, net margin 0.0%.

Higher leverage with weak momentum and thin margins can amplify drawdown severity.

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Mineralys Therapeutics, Inc. Market vs Earnings Trajectory

MLYS ยท NASDAQ

Loading price and EPS data...

Mineralys Therapeutics, Inc.

Mineralys Therapeutics, Inc. Fair Value Envelope

MLYS ยท NASDAQ

Our analysis suggests that MLYS has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $25.06, this represents a potential HIDDEN relative to our calculated worth for Mineralys Therapeutics, Inc..

Intrinsic Value
Current Price: $25.06
3Y-60.0%
5Y+209.0%
10Y+209.0%

No Revenue Data

MLYS has not reported any revenue values in the available annual periods.

3Y+419.0%
5Y+4414.0%
10Y+4414.0%
3Y+387.0%
5Y+5682.0%
10Y+5682.0%
3Y+387.0%
5Y+5683.0%
10Y+5683.0%
3Y+478.0%
5Y+44436.0%
10Y+44436.0%
Mineralys Therapeutics, Inc.

Mineralys Therapeutics, Inc. Profit Bridge

MLYS ยท NASDAQ
Revenue0.00
Cost of Goods Sold (59.00K)
Gross Profit-59.00K
Operating Expenses (170.60M)
Operating Income-170.60M
Interest Expense (0.00)
Other Income/Expense15.95M
Pretax Income-154.65M
Income Tax (0.00)
Net Income-154.65M
Net Income
-154.65M

Profitability Analysis

No Gross Profit Margin Data

MLYS has not reported any gross profit margin values in the available annual periods.

No Operating Profit Margin Data

MLYS has not reported any operating profit margin values in the available annual periods.

No Net Profit Margin Data

MLYS has not reported any net profit margin values in the available annual periods.

-23.91%
Return on Equity
-74%
3Y-142.0%
5Y-125.0%
10Y-125.0%
-23.37%
Return on Assets
-73%
3Y-10.0%
5Y-90.0%
10Y-90.0%
-26.38%
Return on Invested Capital
-74%
3Y-11.0%
5Y-92.0%
10Y-92.0%
MLYS

Mineralys Therapeutics, Inc. Cash Conversion Engine

MLYS ยท NASDAQ
Net Income-154.65M
Depreciation & Amortization59.00K
Stock-Based Compensation19.32M
Change in Working Capital2.73M
Others-9.88M
Capital Expenditures-15.00K
Free Cash Flow-142.43M

Cash Flow Quality Analysis

FCF Conversion Rate

92.1%

Strong cash conversion. Most reported earnings translate into actual cash flow, suggesting solid fundamentals.

CapEx Intensity

-0.0%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

+14.4%

Steady FCF growth indicates consistent cash generation improvement. On a positive trajectory.

Working Capital Impact

+$2.73M

Working capital inflow boosted cash flow. Efficient management of receivables, inventory, and payables contributing positively.

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Mineralys Therapeutics, Inc. Funding & Solvency Profile

MLYS ยท NASDAQ
Cash & Cash Equivalents112.78M
Net Receivables0.00
Inventory0.00
Other Current Assets539.69M
Total Current Assets652 M
Property, Plant & Equipment32.00K
Goodwill & Intangible Assets0.00
Long-Term Investments0.00
Other Non-Current Assets360.00K
Total Non-Current Assets392 K
Total Assets
652.86M

Financial Health Analysis

Current Ratio

44.33x

Excellent liquidity position. The company can easily cover its short-term obligations with substantial cushion.

Debt-to-Equity Ratio

0.02x

Conservative capital structure. The company relies primarily on equity financing, indicating low financial risk.

Working Capital

638 M

Strong working capital position provides significant operational flexibility and financial cushion.

Asset Composition

100% Current

Asset-light business model with high liquidity. Majority of assets are easily convertible to cash.

Financial Health Insight

Strong financial foundation: Excellent liquidity combined with conservative leverage suggests the company is well-positioned to weather economic uncertainties and fund growth opportunities.

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Mineralys Therapeutics, Inc. Street Expectations Map

MLYS ยท NASDAQ

Wall Street analysts project that MLYS stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 46.00, with estimates ranging from a low of 30.00 to a high of 56.00.

Lowest Target
30.00
19.71%
Consensus Target
46.00
83.56%
Highest Target
56.00
123.46%

The consensus 1-year price target stands at 46.00, with estimates ranging from a low of 30.00 to a high of 56.00.

Analyst Consensus Analysis

Upside Potential

+83.6%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

56.5% spread

Mixed analyst views. Wide target range suggests differing opinions on key value drivers, growth prospects, or risk factors.

Analyst Conviction

Low

Bearish or uncertain outlook. Limited upside or poor consensus suggests challenges ahead or fundamental concerns.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

mlys

Mineralys Therapeutics, Inc. Insider Positioning

MLYS ยท NASDAQ

During the last 12 months, insiders have purchased $53.76M and sold $60.75M worth of MLYS shares, resulting in $6.98M of net selling activity.

3 Months

Bought

369.0K

8.76M

Sold

100.7K

2.72M

Net Activity

+6.0M

+$6.04M

3-6 Months

Bought

0

0.00

Sold

246.3K

8.54M

Net Activity

-8.5M

-$8.54M

6-9 Months

Bought

0

0.00

Sold

1.1M

48.30M

Net Activity

-48.3M

-$48.30M

9-12 Months

Bought

1.8M

45.00M

Sold

82.9K

1.18M

Net Activity

+43.8M

+$43.81M

Top Buyers

1
RCML

Ra Capital Management, L.P.

Director

1.5M sharesโ€ข3 transactions

$38.76M

2
AS

Akkaraju Srinivas

Director

588.2K sharesโ€ข1 transactions

$15.00M

Top Sellers

1
SBT

Slingsby Brian Taylor

Director, 10 Percent Owner:

1.0M sharesโ€ข1 transactions

$43.35M

2
RDM

Rodman David Malcom

Officer: Chief Medical Officer

349.4K sharesโ€ข25 transactions

$11.05M

3
CJ

Congleton Jon

Director, Officer: Chief Executive Officer

94.5K sharesโ€ข6 transactions

$3.05M

4
LAS

Levy Adam Scott

Officer: Cfo And Secretary

69.0K sharesโ€ข6 transactions

$2.15M

5
GAM

Gold Alexander M

Director

19.7K sharesโ€ข3 transactions

$919K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Slightly bearish with $6.98M net selling. Selling modestly exceeds buying, which could be routine diversification rather than concern.

Buy/Sell Ratio

0.89:1

Moderately negative ratio. Selling is roughly double the buying, which may be routine or signal caution.

Recent Trend (3 Months)

$6.04M

Very strong recent buying momentum. Recent insider purchases significantly outpace sales, suggesting near-term optimism.

Insider Participation

High Selling

5 insider sellers vs. 2 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Balanced insider activity: Roughly equal buying and selling suggests normal portfolio management rather than strong directional signals. Look to other metrics for clearer investment insights.

No Dividend Yield Data

MLYS has not reported any dividend yield values in the available annual periods.

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mlys Dividend History

MLYS
10Y CAGR +0%
Latest $0
Annual $0
Stable dividend payments
Last Period: +0%