Madrigal Pharmaceuticals, Inc.

Madrigal Pharmaceuticals, Inc.

MDGL·NASDAQ

$488.15

+7.8%
HealthcareBiotechnology

Madrigal Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapeutic candidates for the treatment of cardiovascular, metabolic, and liver diseases. Its lead product candidate is resmetirom, a liver-directed selective thyroid hormone receptor-ß agonist, which is in Phase III clinical trials for the treatment of non-alcoholic steatohepatitis. The company also develops MGL-3745, a backup compound to resmetirom. It has research, development, and commercialization agreement with Hoffmann-La Roche. Madrigal Pharmaceuticals, Inc. is headquartered in West Conshohocken, Pennsylvania.

At a Glance

Live Snapshot
Market Cap$11.25B
EPS-12.8500
P/E Ratio-37.99
Earnings Date08/04/2026
-31.58%
Return on Invested Capital
-45%
3Y-73.0%
5Y-63.0%
10Y-54.0%
-47.83%
Return on Equity
-23%
3Y-68.0%
5Y-43.0%
10Y-34.0%
-22.89%
Return on Assets
-49%
3Y-72.0%
5Y-68.0%
10Y-64.0%
Madrigal Pharmaceuticals, Inc.

Madrigal Pharmaceuticals, Inc. Management Team

MDGL · NASDAQ
MW

Mr. William J. Sibold

Chief Executive Officer, President & Director

Compensation

$1,850,446

Born 1966(Age 60)
male
MT

Ms. Tina E. Ventura

Chief Investor Relations Officer

female
MC

Ms. Carole Huntsman

Executive Vice President & Chief Commercial Officer

Compensation

$870,825

Born 1965(Age 61)
female
MM

Ms. Mardi C. Dier

Executive Vice President & Chief Financial Officer

Compensation

$934,681

Born 1964(Age 62)
female
MC

Mr. Clint Wallace

Executive Vice President & Chief Human Resources Officer

male
MR

Mr. Ronald Filippo

Executive Vice President & Chief Information Officer

male
MM

Mr. Mark Underwood

Executive Vice President of Business Planning & Operations

male
MS

Ms. Shannon Kelley

Executive Vice President, Chief Legal Officer & Corporate Secretary

Compensation

$782,208

Born 1975(Age 51)
female
DR

Dr. Rebecca A. Taub M.D.

Founder, Senior Scientific & Medical Advisor and Director

Compensation

$1,072,209

Born 1952(Age 74)
ME

Mr. Edward Chiang

Senior Vice President of Clinical & Technical Operations

male
mdgl

Madrigal Pharmaceuticals, Inc. Insider Positioning

MDGL · NASDAQ

During the last 12 months, insiders have purchased $245K and sold $13.11M worth of MDGL shares, resulting in $12.86M of net selling activity.

3 Months

Bought

0

0.00

Sold

2.6K

1.25M

Net Activity

-1.3M

-$1.25M

3-6 Months

Bought

0

0.00

Sold

2.7K

1.30M

Net Activity

-1.3M

-$1.30M

6-9 Months

Bought

0

0.00

Sold

11.0K

5.34M

Net Activity

-5.3M

-$5.34M

9-12 Months

Bought

657

245.24K

Sold

14.3K

5.22M

Net Activity

-5.0M

-$4.98M

Top Buyers

1
BBAL

Baker Bros. Advisors Lp

Director

657 shares2 transactions

$245K

Top Sellers

1
SWJ

Sibold William John

Director, Officer: President And Ceo

10.8K shares3 transactions

$5.08M

2
FPA

Friedman Paul A

Director

9.3K shares8 transactions

$3.54M

3
TR

Taub Rebecca

Director

3.9K shares5 transactions

$1.38M

4
DM

Dier Mardi

Officer: Evp And Cfo

2.1K shares3 transactions

$967K

5
SD

Soergel David

Officer: Chief Medical Officer

1.9K shares2 transactions

$952K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $12.86M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.02:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$1.25M

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

MDGL - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 28, 2026
June 17, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 29, 2025
June 20, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 29, 2024
June 25, 2024
2024
DEF 14A

DEF 14A

N/A

May 01, 2023
May 01, 2023
 
DEF 14A

DEF 14A 2022

N/A

May 02, 2022
June 15, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 30, 2021
June 17, 2021
2021
DEF 14A

DEF 14A 2020

N/A

April 29, 2020
June 17, 2020
2020
DEF 14A

DEF 14A 2019

N/A

May 15, 2019
June 27, 2019
2019
DEF 14A

DEF 14A 2018

N/A

April 27, 2018
June 19, 2018
2018
DEF 14A

DEF 14A 2017

N/A

April 28, 2017
June 29, 2017
2017
Showing 1 to 10 of 18 filings