Martin M. McGlynn
Thanks Greg. So this afternoon I’ll limited my prepared remarks, to the notable progress in our clinical translational efforts. Since our last call on March 12 and what you should be looking for, for the rest of 2014 as it unfolds. So let’s start with the progress report. We achieved a major milestone for the company when we completed enrollment in the 12 patient Phase I/II thoracic spinal cord injury trial. This trial enrolls seven patients with no motor or sensory function below the side of injury; these are classified as AIS A patients. And five patients with no motor function and limited sensory function below the side of injury otherwise classified as AIS B according to the American Spinal Injury Association Impairment Scale. So this brings the 30 the total number of patients who have been successfully transplanted that the companies proprietary expandable HuCNS-SC sales. Secondly, in our geographic atrophy of age-related macular degeneration clinical trial, we received the green light from an independent data monitoring committee after a through review of all of the available data to proceed to transplanting the last eight patients in cohort II in the companies 16 patient Phase I/II trial. Age-related macular degeneration is the leading cost of blindness in elderly. And you may recall that the eight patients in cohort I are in a very advance stage of the diseases with very poor vision. The first four patients received the low-dose of 200,000 cells into the most affected eye, while the second group or four received 1 million cells. The eight patients to be transplanted now in cohort II will each receive 1 million cells into the most affected eye excuse me however their condition will be less severe than those enrolled in the first cohort. Thirdly, we finalized the design of a randomized controlled Phase II clinical trial in spinal cord injury, and we’ve made significant progress in the planning and preparation for this trial, which is planned to begin later this year. Now as I mentioned in our last call, this study will involve patients with injury to the cervical spinal cord, which usually results in loss of both arm and leg function. These patients account for approximately 60% of all spinal cord injuries. The end points in this trial will focus on measuring direct changes in strength and function of the upper extremities. Now, it’s important to remember that even slight improvements in motor function, can result in significant quality of life improvements for patient suffering from spinal cord injuries as well as substantial savings to the healthcare system. So turning now for the rest of 2014, you should look for the company to do a number of things. Number one, to provide clinical trial updates from the ongoing Phase I/II trial in drastic spinal cord injury. Dr. Armin Curt, the Principal Investigator for the trial at Balgrist Hospital in