Ligand Pharmaceuticals Incorporated

Ligand Pharmaceuticals Incorporated

LGND·NASDAQ

$234.40

+0.77%
HealthcareBiotechnology

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, focuses on developing or acquiring technologies that help pharmaceutical companies to discover and develop medicines worldwide. Its commercial programs include Kyprolis and Evomela, which are used to treat multiple myeloma; Veklury for the treatment of moderate or severe COVID-19; Teriparatide injection product for osteoporosis; Vaxneuvance for the prevention of invasive disease caused by Streptococcus pneumoniae; and Pneumosil, a pneumococcal conjugate vaccine to help fight against pneumococcal pneumonia among children. The company also offers Rylaze, a recombinant erwinia asparaginase for the treatment of acute lymphoblastic leukemia or lymphoblastic lymphoma in adult and pediatric patients; and Nexterone, a captisol-enabled formulation of amiodarone; and Zulresso, a captisol-enabled formulation of brexanolone for the treatment of postpartum depression. In addition, it provides Noxafil-IV, a captisol-enabled formulation of posaconazole for IV use; Duavee for the treatment of postmenopausal osteoporosis; Aziyo portfolio of commercial pericardial repair and CanGaroo envelope extracellular matrix products; Exemptia for autoimmune diseases; Vivitra for breast cancer; Bryxta and Zybev for various indications; and Minnebro for the treatment of hypertension. The company's partners and licenses programs, which are in clinical development used for the treatment of cancer, seizure, diabetes, cardiovascular disease, muscle wasting, liver and kidney disease, and other diseases. Further, it sells Captisol materials. The company was incorporated in 1987 and is headquartered in Emeryville, California.

At a Glance

Live Snapshot
Market Cap$4.70B
EPS6.4400
P/E Ratio36.40
Earnings Date08/06/2026
2.42%
Return on Invested Capital
-39%
3Y-4181.0%
5Y-18.0%
10Y-209.0%
12.23%
Return on Equity
-2620%
3Y-319.0%
5Y-3008.0%
10Y-2874.0%
7.97%
Return on Assets
-1963%
3Y-282.0%
5Y-3740.0%
10Y-3033.0%
Ligand Pharmaceuticals Incorporated

Ligand Pharmaceuticals Incorporated Management Team

LGND · NASDAQ
MT

Mr. Todd C. Davis Ph.D.

Chief Executive Officer & Director

Compensation

$1,342,794

Born 1961(Age 65)
male
MS

Mr. Scott M. Plesha

Chief Executive Officer of Pelthos Therapeutics

Born 1965(Age 61)
male
MO

Mr. Octavio Espinoza

Chief Financial Officer

Compensation

$726,930

Born 1971(Age 55)
male
MA

Mr. Andrew T. Reardon J.D.

Chief Legal Officer & Secretary

Compensation

$699,330

Born 1975(Age 51)
male
MP

Mr. Patrick Lucy

Senior Vice President & CBO Protein Expression Business

male
DK

Dr. Keith Marschke Ph.D.

Senior Vice President of Biology & Scientific Affairs

MR

Mr. Richard B. Baxter

Senior Vice President of Investment Operation

male
MP

Mr. Paul J. Hadden

Senior Vice President of Investments & Business Development

male
DK

Dr. Karen R. Reeves M.D.

Senior Vice President of Investments & Head of Clinical Strategy

Born 1951(Age 75)
DV

Dr. Vincent D. Antle Ph.D.

Senior Vice President of Technical Operations & QA - Capitsol

Born 1969(Age 57)
lgnd

Ligand Pharmaceuticals Incorporated Insider Positioning

LGND · NASDAQ

During the last 12 months, insiders have sold $3.98M worth of LGND shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

7.5K

1.62M

Net Activity

-1.6M

-$1.62M

3-6 Months

Bought

0

0.00

Sold

4.0K

789.96K

Net Activity

-790K

-$790K

6-9 Months

Bought

0

0.00

Sold

6.3K

1.26M

Net Activity

-1.3M

-$1.26M

9-12 Months

Bought

0

0.00

Sold

2.5K

306.61K

Net Activity

-307K

-$307K

Top Buyers

No buying activity

Top Sellers

1
EO

Espinoza Octavio

Officer: Chief Financial Officer

4.9K shares2 transactions

$1.03M

2
LJL

Lamattina John L

Director

4.2K shares2 transactions

$852K

3
GNR

Gray Nancy Ryan

Director

3.0K shares1 transactions

$619K

4
SSL

Sabba Stephen L

Director

3.0K shares2 transactions

$618K

5
RA

Reardon Andrew

Officer: Clo & Secretary

2.2K shares5 transactions

$381K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $3.98M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$1.62M

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

LGND - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2025

N/A

April 21, 2026
December 31, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 22, 2025
December 31, 2024
2024
DEF 14A

DEF 14A 2023

N/A

April 25, 2024
December 31, 2023
2023
DEF 14A

DEF 14A

N/A

April 20, 2023
April 20, 2023
 
DEF 14A

DEF 14A 2022

N/A

April 22, 2022
June 10, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 23, 2021
June 04, 2021
2021
DEF 14A

DEF 14A 2020

N/A

November 12, 2020
December 15, 2020
2020
DEF 14A

DEF 14A 2020

N/A

April 24, 2020
April 24, 2020
2020
DEF 14A

DEF 14A 2019

N/A

April 24, 2019
June 06, 2019
2019
DEF 14A

DEF 14A 2018

N/A

April 30, 2018
April 27, 2018
2018
Showing 1 to 10 of 31 filings