Krystal Biotech, Inc.

Krystal Biotech, Inc.

KRYSยทNASDAQ

$301.82

+0.74%
HealthcareBiotechnology

Krystal Biotech, Inc., a clinical stage biotechnology company, engages in the field of redosable gene therapy to treat serious rare diseases in the United States. Its lead product candidate is beremagene geperpavec (B-VEC), which is in Phase III clinical study to treat dystrophic epidermolysis bullosa. The company is also involved in developing KB105 that is in Phase I/II clinical study for treating patients with deficient autosomal recessive congenital ichthyosis; KB301, which is in Phase I/II clinical stage for treating wrinkles and other presentations of aged or damaged skin; KB407 that is in preclinical stage for cystic fibrosis; and KB104, which is in preclinical stage for netherton syndrome. Its discovery stage product candidates include KB5xx for treating chronic skin diseases, KB3xx to treat aesthetic skin conditions, and KB3xx product. Krystal Biotech, Inc. was founded in 2015 and is headquartered in Pittsburgh, Pennsylvania.

At a Glance

Live Snapshot
Market Cap$8.90B
EPS7.0800
P/E Ratio42.63
Earnings Date08/03/2026
3Y-300.0%
5Y-870.0%
10Y-15422.0%
3Y-49.0%
5Y+422.0%
10Y+389347.0%
3Y-75.0%
5Y-93.0%
10Y+168.0%
KRYS

Krystal Biotech, Inc. Cash Conversion Engine

KRYS ยท NASDAQ
Net Income204.83M
Depreciation & Amortization6.55M
Stock-Based Compensation54.51M
Change in Working Capital-36.42M
Others-5.77M
Capital Expenditures-11.95M
Free Cash Flow188.91M

Cash Flow Quality Analysis

FCF Conversion Rate

92.2%

Strong cash conversion. Most reported earnings translate into actual cash flow, suggesting solid fundamentals.

CapEx Intensity

5.9%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

+58.5%

Strong FCF growth demonstrates improving cash generation and business momentum. Positive signal for sustainability.

Working Capital Impact

-$36.42M

Minimal working capital impact on FCF. Changes in operating assets and liabilities well-managed.

Cash Flow Quality Insight

Asset-light with strong cash conversion: Low capital requirements combined with efficient cash generation creates significant shareholder value through dividends, buybacks, or strategic investments.

Krystal Biotech, Inc. Cash Flow Statement

KRYS โ€ข NASDAQ

Krystal Biotech, Inc. Cash Flow StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018Dec 2017Dec 2016
OPERATING ACTIVITIES
204.8M
89.2M
10.9M
-140M
-69.6M
-32.2M
-19.1M
-10.9M
-7.9M
-1.2M
6.6M
6.7M
5M
4.1M
2.8M
1.9M
748K
141K
23K
2K
-22.8M
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
54.5M
49.1M
39.9M
33.2M
15.3M
3.3M
1.2M
792K
246K
33K
-5.8M
-7.1M
-106.8M
-690K
1.5M
33K
67K
962K
3.3M
7K
(0.0)
(5.7M)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-36.4M
-14.5M
-37.9M
2.8M
2.1M
928K
-1.7M
511K
498K
-203K
200.9M
123.4M
-88.8M
-100.6M
-47.9M
-26.1M
-18.7M
-9.4M
-3.9M
-1.3M
INVESTING ACTIVITIES
-12M
-4.2M
-11.8M
-53M
-68.3M
-14.8M
-6.4M
-2.2M
-210K
-15K
(435K)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-422.5M
-457.7M
-508.8M
-318.8M
-190.5M
-3.2M
-9.1M
-8.1M
(0.0)
(0.0)
375.6M
298.5M
503.2M
257.7M
32M
6.9M
10.5M
0.0
0.0
0.0
0.0
0.0
100M
0.0
0.0
0.0
0.0
0.0
0.0
0.0
-58.4M
-163.4M
(82.6M)
-114.1M
-226.8M
-11.2M
-5M
-10.3M
-210K
-15K
FINANCING ACTIVITIES
22.7M
32.4M
203.5M
36M
355.6M
118M
107.5M
73.8M
42.5M
100K
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
2.3M
1.8M
-14M
-5.4M
-749K
-649K
-8M
0.0
0.0
0.0
0.0
0.0
8.7M
27M
202.8M
35.3M
347.7M
118M
107.5M
73.8M
51.8M
3.2M
CASH FLOW SUMMARY
286K
-458K
-156K
-41K
0.0
0.0
0.0
0.0
0.0
0.0
151.4M
-13.5M
196.4M
-179.3M
73M
80.8M
83.8M
54.1M
47.7M
1.9M
344.9M
358.3M
161.9M
341.2M
268.3M
187.5M
103.7M
49.6M
1.9M
0.0
496.3M
344.9M
358.3M
161.9M
341.2M
268.3M
187.5M
103.7M
49.6M
1.9M
188.9M
119.2M
-100.6M
-153.5M
-116.3M
-40.9M
-25.1M
-11.7M
-4.1M
-1.3M

SEC Filings

KRYS - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
8-K

8-K 2026

N/A

May 20, 2026
May 15, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 04, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 04, 2026
May 04, 2026
2026
DEF 14A

DEF 14A 2026

N/A

April 03, 2026
April 03, 2026
2026
8-K

8-K 2026

N/A

February 17, 2026
February 17, 2026
2026
10-K

10-K 2025 FY

FY

February 17, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

January 12, 2026
January 11, 2026
2026
8-K

8-K 2026

N/A

January 08, 2026
January 08, 2026
2026
8-K

8-K 2025

N/A

December 23, 2025
December 23, 2025
2025
8-K

8-K 2025

N/A

November 03, 2025
November 03, 2025
2025
Showing 1 to 10 of 157 filings