OG

Opus Genetics, Inc.

IRDยทNASDAQ

$4.20

+5.3%
HealthcareBiotechnology

Opus Genetics, Inc., a clinical-stage ophthalmic biopharmaceutical company, focuses on developing and commercializing therapies for the treatment of unmet needs of patients with refractive and retinal eye disorders. The company offers Phentolamine Ophthalmic Solution for reversal of mydriasis, as well as is in Phase III clinical trials for presbyopia and dim light or night vision disturbances. Its lead retinal product candidate is APX3330, a small-molecule inhibitor of reduction oxidation effector factor-1 protein that has completed Phase II clinical trial for the treatment of diabetic retinopathy. The company also develops APX2009 and APX2014 that are preclinical product candidates for retina indications. The company was formerly known as Ocuphire Pharma, Inc. Opus Genetics, Inc. was founded in 2018 and is headquartered in Farmington Hills, Michigan.

At a Glance

Live Snapshot
Market Cap$341.86M
EPS-0.8000
P/E Ratio-5.25
Earnings Date08/12/2026
-90.90%
Return on Invested Capital
-63%
3Y-335.0%
5Y-34.0%
10Y-141.0%
-323.11%
Return on Equity
-62%
3Y-935.0%
5Y-277.0%
10Y-496.0%
-98.70%
Return on Assets
-37%
3Y-370.0%
5Y-29.0%
10Y-71.0%
OG

Opus Genetics, Inc. Management Team

IRD ยท NASDAQ
MG

Mr. George Magrath M.B.A., M.D., M.S.

Chief Executive Officer & Director

Compensation

$889,238

Born 1984(Age 42)
male
MN

Mr. Nirav Suresh Jhaveri C.F.A.

Chief Financial Officer

Compensation

$575,916

Born 1978(Age 48)
male
MJ

Mr. Joseph K. Schachle MBA

Chief Operating Officer

Born 1965(Age 61)
male
DA

Dr. Ashwath Jayagopal Ph.D.

Chief Scientific & Development Officer

Compensation

$565,368

Born 1982(Age 44)
ME

Mr. Erik Sims

Director & Corporate Controller

male
MB

Ms. Bindu Manne

Head of Market Development & Commercialization

female
DB

Dr. Benjamin R. Yerxa Ph.D.

President & Director

Born 1966(Age 60)
MB

Mr. Bernhard Hoffmann M.B.A.

Senior Vice President of Corporate Development & Secretary

Compensation

$434,100

Born 1956(Age 70)
male
MA

Ms. Amy Zaremba Rabourn C.P.A., MAcc

Senior Vice President of Finance

Compensation

$434,100

Born 1981(Age 45)
female
i

Opus Genetics, Inc. Insider Positioning

IRD ยท NASDAQ

During the last 12 months, insiders have purchased $1.26M and sold $16.49M worth of IRD shares, resulting in $15.23M of net selling activity.

3 Months

Bought

0

0.00

Sold

1.8M

7.78M

Net Activity

-7.8M

-$7.78M

3-6 Months

Bought

81.0K

160.27K

Sold

4.0M

8.60M

Net Activity

-8.4M

-$8.44M

6-9 Months

Bought

0

0.00

Sold

54.1K

116.20K

Net Activity

-116K

-$116K

9-12 Months

Bought

956.5K

1.10M

Sold

0

0.00

Net Activity

+1.1M

+$1.10M

Top Buyers

1
GC

Gallagher Cam

Director

950.6K sharesโ€ข2 transactions

$1.16M

2
AS

Ainsworth Sean

Director

87.0K sharesโ€ข1 transactions

$100K

Top Sellers

1
FFBRDF

Foundation Fighting Blindness Retinal Degeneration Fund

Director, Other: See Remarks

5.7M sharesโ€ข2 transactions

$15.99M

2
MG

Magrath George

Director, Officer: Chief Executive Officer

64.3K sharesโ€ข3 transactions

$247K

3
YBR

Yerxa Benjamin R

Director, Officer: President

31.3K sharesโ€ข2 transactions

$86K

4
JA

Jayagopal Ashwath

Officer: Chief Scientific & Dev. Ofc.

11.3K sharesโ€ข2 transactions

$58K

5
SJK

Schachle Joseph K

Officer: Chief Operating Officer

8.4K sharesโ€ข2 transactions

$44K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $15.23M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.08:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$7.78M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 2 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

IRD - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

March 23, 2026
April 20, 2026
2026
DEF 14A

DEF 14A 2024

N/A

April 29, 2024
June 11, 2024
2024
DEF 14A

DEF 14A 2023

N/A

May 01, 2023
June 06, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 27, 2022
June 13, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 26, 2021
June 07, 2021
2021
DEF 14A

DEF 14A 2019

N/A

April 29, 2019
June 06, 2019
2019
DEF 14A

DEF 14A 2019

N/A

February 14, 2019
March 26, 2019
2019
DEF 14A

DEF 14A 2018

N/A

July 23, 2018
August 30, 2018
2018
DEF 14A

DEF 14A 2018

N/A

April 23, 2018
June 14, 2018
2018
DEF 14A

DEF 14A 2017

N/A

February 24, 2017
April 11, 2017
2017
Showing 1 to 10 of 21 filings