Iovance Biotherapeutics, Inc.

Iovance Biotherapeutics, Inc.

IOVAยทNASDAQ

$3.79

-7.6%
HealthcareBiotechnology

Iovance Biotherapeutics, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing cancer immunotherapy products to harness the power of a patient's immune system to eradicate cancer cells. It has six ongoing phase 2 clinical studies, including C-144-01, of its lead product candidate, lifileucel, for the treatment of metastatic melanoma; C-145-04, of its product candidate lifileucel for recurrent, metastatic, or persistent cervical cancer; and C-145-03, of its product candidate LN-145, for recurrent and/or metastatic head and neck squamous cell carcinoma. Iovance Biotherapeutics, Inc. has collaborations and licensing agreements with H. Lee Moffitt Cancer Center; M.D. Anderson Cancer Center; Ohio State University; Centre hospitalier de l'Universitรฉ de Montreal; Cellectis S.A.; and Novartis Pharma AG. The company was formerly known as Lion Biotechnologies, Inc. and changed its name to Iovance Biotherapeutics, Inc. in June 2017. Iovance Biotherapeutics, Inc. was incorporated in 2007 and is headquartered in San Carlos, California.

At a Glance

Live Snapshot
Market Cap$1.36B
EPS-1.0900
P/E Ratio-3.48
Earnings Date08/06/2026
3Y+3.0%
5Y+47.0%
10Y+826.0%
3Y-81.0%
5Y-115.0%
10Y+434.0%
3Y+58.0%
5Y-48.0%
10Y+210.0%
IOVA

Iovance Biotherapeutics, Inc. Cash Conversion Engine

IOVA ยท NASDAQ
Net Income-390.98M
Depreciation & Amortization34.46M
Stock-Based Compensation61.58M
Change in Working Capital-24.27M
Others18.87M
Capital Expenditures-33.84M
Free Cash Flow-336.24M

Cash Flow Quality Analysis

FCF Conversion Rate

86.0%

Strong cash conversion. Most reported earnings translate into actual cash flow, suggesting solid fundamentals.

CapEx Intensity

-11.2%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

+7.6%

Steady FCF growth indicates consistent cash generation improvement. On a positive trajectory.

Working Capital Impact

-$24.27M

Minimal working capital impact on FCF. Changes in operating assets and liabilities well-managed.

Cash Flow Quality Insight

Working capital strain: Significant cash tied up in operations. Monitor receivables collection, inventory turns, and payment terms to optimize cash conversion cycle.

Iovance Biotherapeutics, Inc. Cash Flow Statement

IOVA โ€ข NASDAQ

Iovance Biotherapeutics, Inc. Cash Flow StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018Dec 2017Dec 2016Dec 2015Dec 2014Dec 2013Dec 2012Dec 2011Dec 2010Dec 2009Dec 2008
OPERATING ACTIVITIES
-391M
-372.2M
-444M
-395.9M
-342.3M
-259.6M
-197.6M
-123.6M
-92.1M
-52.9M
-27.7M
-12M
-25.4M
-3.3M
-25.7M
-1.6M
-15.8K
-57.1K
34.5M
43.6M
33.1M
21.1M
14M
1.1M
1.2M
956K
952K
978K
999K
88.2K
7.1K
6.2K
2.7K
58.6K
1.3K
1.3K
-2.1M
-2.8M
-3.5M
0.0
0.0
1.9M
-3.4M
0.0
0.0
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0.0
0.0
0.0
0.0
0.0
61.6M
109.6M
62.6M
84M
69.8M
40.9M
24.3M
20M
12M
18.9M
8.5M
3.8M
19.7M
3.3M
0.0
0.0
0.0
0.0
18.9M
-8.6M
-3.5M
871K
6M
7.6M
6.6M
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19K
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8.5M
3.8M
22M
-3.4M
19.1M
906.6K
0.0
0.0
-24.3M
-122.6M
-6.5M
-2.9M
24.6M
3M
10M
2.7M
416K
418K
-243K
-500.6K
-264.3K
4.5M
359.8K
22K
-8.0
-1.5K
-302.4M
-353M
-361.8M
-292.8M
-227.9M
-205.1M
-158.9M
-101.2M
-78.7M
-32.7M
-18.4M
-8.6M
-3.7M
-2.2M
-6.2M
-620.8K
-14.4K
-57.3K
INVESTING ACTIVITIES
-33.8M
-11.1M
-22.3M
-20.4M
-37.6M
-46.8M
-6.9M
-1.2M
-1M
-1.5M
-1.1M
-1.6M
-12.7K
(0.0)
-31.1K
(0.0)
(0.0)
(0.0)
(0.0)
-52.6M
-212.6M
-276.9M
-37.7M
(271.1M)
-96.9M
(0.0)
(0.0)
(0.0)
(19.9M)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-318.7M
-460.8M
-205.9M
-245.8M
-725.2M
-947.7M
-417.7M
-426.1M
(0.0)
-110.2M
-160.6M
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
400M
428M
285.6M
522.7M
762.9M
676.6M
514.6M
41M
59.7M
120.7M
70.6M
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
276.9M
37.7M
-271.1M
96.9M
-385.1M
59.7M
10.4M
-19.9M
0.0
-12.7K
0.0
-50K
0.0
0.0
0.0
(47.5M)
-96.4M
-155.2M
(256.5M)
(132K)
-317.9M
(90M)
-386.3M
(58.7M)
(8.9M)
-91.2M
-1.6M
-12.7K
(0.0)
-81.1K
(0.0)
(0.0)
(0.0)
FINANCING ACTIVITIES
307.8M
397.3M
463.3M
189.5M
203.2M
567M
0.0
398.8M
0.0
0.0
68.3M
32.2M
7.1M
250K
873K
1.9M
0.0
0.0
0.0
0.0
0.0
0.0
1M
0.0
0.0
0.0
0.0
0.0
0.0
0.0
311K
1.5M
4.6M
0.0
0.0
0.0
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-49.5M
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
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(0.0)
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(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-312K
(0.0)
-1.3M
-642K
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-7.1M
-6.6M
-322K
648K
35.1M
9.4M
6.1M
-373.3M
5M
50.7M
-58.3M
-29M
1.1K
0.0
0.0
-5K
19.8K
2.5K
300.8M
390.7M
463M
190.2M
239.3M
576.4M
6.1M
424.3M
58.7M
96.9M
78.3M
35.5M
23.3M
1.7M
5.5M
1.9M
19.8K
0.0
CASH FLOW SUMMARY
1.5M
-541K
-2.7M
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
47.4M
-59.3M
-56.8M
153.8M
11.5M
53.4M
-62.7M
-63.2M
38.7M
73.1M
-31.3M
25.2M
19.7M
-510.2K
-782.3K
1.3M
5.4K
-57.3K
122.1M
181.3M
238.2M
84.3M
72.9M
19.4M
82.2M
145.4M
106.7M
33.6M
44.9M
19.7M
0.0
510.2K
1.3M
8.3K
2.9K
60.2K
169.1M
122.1M
181.3M
238.2M
84.3M
72.9M
19.4M
82.2M
145.4M
106.7M
13.6M
44.9M
19.7M
0.0
510.2K
1.3M
8.3K
2.9K
-336.2M
-364M
-384.1M
-313.2M
-265.5M
-251.9M
-165.8M
-102.4M
-79.7M
-34.2M
-19.5M
-10.2M
-3.7M
-2.2M
-6.2M
-620.8K
-14.4K
-57.3K

SEC Filings

IOVA - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
8-K

8-K 2026

N/A

May 07, 2026
May 07, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 07, 2026
March 31, 2026
2026
DEF 14A

DEF 14A 2026

N/A

April 28, 2026
June 10, 2026
2026
8-K

8-K 2026

N/A

March 20, 2026
March 17, 2026
2026
8-K

8-K 2026

N/A

February 24, 2026
February 24, 2026
2026
10-K

10-K 2025 FY

FY

February 24, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

January 09, 2026
January 09, 2026
2026
10-Q

10-Q 2025 Q3

Q3

November 06, 2025
September 30, 2025
2025
8-K

8-K 2025

N/A

November 06, 2025
November 06, 2025
2025
8-K

8-K 2025

N/A

August 29, 2025
August 29, 2025
2025
Showing 1 to 10 of 371 filings