Illumina, Inc.

Illumina, Inc.

ILMNยทNASDAQ

$170.93

+5.2%
HealthcareMedical - Diagnostics & Research

Illumina, Inc. provides sequencing and array-based solutions for genetic and genomic analysis. Its products and services serve customers in a range of markets enabling the adoption of genomic solutions in research and clinical settings for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments. The company provides instruments and consumables used in genetic analysis; and genotyping and sequencing services, instrument service contracts, and development and licensing agreements, as well as cancer detection testing services. Its customers include genomic research centers, academic institutions, government laboratories, and hospitals, as well as pharmaceutical, biotechnology, commercial molecular diagnostic laboratories, and consumer genomics companies. The company markets and distributes its products directly to customers in North America, Europe, Latin America, and the Asia-Pacific region, as well as sells through life-science distributors in various markets within Europe, the Asia-Pacific region, Latin America, the Middle East, and Africa. The company was incorporated in 1998 and is based in San Diego, California.

At a Glance

Live Snapshot
Market Cap$25.86B
EPS5.4800
P/E Ratio31.19
Earnings Date07/30/2026

Intrinsic Alpha Methodology

Thesis Lenses

Signal ยท Driver ยท Risk

Signal

High confidence

Valuation multiple is elevated (P/E 31.2).

Valuation inputs: P/E 31.2, earnings yield +3.2%, momentum +5.2%.

If multiples stay elevated while momentum fades, downside repricing risk rises.

Driver

High confidence

Return profile is strong (ROE +31.2%, ROIC +12.2%).

Profitability stack: net margin +19.6%, ROE +31.2%, ROIC +12.2%.

Quality deterioration often appears in margins before it shows up in headline EPS.

Risk

High confidence

Downside profile looks controlled across current risk inputs.

Risk factors: liabilities/assets +59.0%, momentum +5.2%, net margin +19.6%.

Higher leverage with weak momentum and thin margins can amplify drawdown severity.

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Illumina, Inc. Market vs Earnings Trajectory

ILMN ยท NASDAQ
Current Price
$170.93
EPS (TTM)
$5.54

Performance Analysis

EPS Growth

-30.1%

Declining earnings warrant investigation into business challenges and competitive position.

Price-EPS Relationship

Divergent

Price is rising despite declining earningsโ€”caution advised as valuation may be stretched.

Stock Price Change

+105.5%

Over the 1Y period, stock price has increased by 105.5%.

P/E Ratio (TTM)

31.2x

Elevated P/E indicates investors expect strong future growth.

Key Insight

Despite declining earnings (-30.1%), the stock price has risen (+105.5%). This disconnect suggests investors may be optimistic about future turnaround, but earnings recovery is critical to sustain the valuation.

Illumina, Inc.

Illumina, Inc. Fair Value Envelope

ILMN ยท NASDAQ

Our analysis suggests that ILMN has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $170.93, this represents a potential HIDDEN relative to our calculated worth for Illumina, Inc..

Intrinsic Value
Current Price: $170.93
3Y-120.0%
5Y+23.0%
10Y+74.0%
3Y-5.0%
5Y+34.0%
10Y+81.0%
3Y-119.0%
5Y+30.0%
10Y+84.0%
3Y+175.0%
5Y-
10Y+57.0%
3Y+778.0%
5Y+4.0%
10Y+124.0%
3Y-46.0%
5Y-12.0%
10Y+55.0%
Illumina, Inc.

Illumina, Inc. Profit Bridge

ILMN ยท NASDAQ
Revenue4.34B
Cost of Goods Sold (1.45B)
Gross Profit2.89B
Operating Expenses (2.03B)
Operating Income864.00M
Interest Expense (101.00M)
Other Income/Expense222.00M
Pretax Income1.09B
Income Tax (236.00M)
Net Income850.00M
Net Income
850.00M

Profitability Analysis

Gross Margin

66.7%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

19.9%

Healthy operating margins demonstrate effective cost control and strong business fundamentals.

Net Profit Margin

19.6%

Strong net margins indicate efficient operations and favorable tax/interest management.

Effective Tax Rate

21.7%

Moderate tax rate typical for most corporations. Represents standard tax burden on profits.

Profitability Insight

High margin compression: Large gap between gross and net margins suggests operational inefficiencies or heavy debt burden. Focus on expense management and deleveraging.

66.49%
Gross Profit Margin
3Y+9.0%
5Y-5.0%
10Y-
19.92%
Operating Profit Margin
3Y-184.0%
5Y-833.0%
10Y-10.0%
19.58%
Net Profit Margin
3Y-176.0%
5Y+16.0%
10Y-26.0%
31.22%
Return on Equity
3Y-254.0%
5Y+340.0%
10Y+22.0%
12.79%
Return on Assets
3Y-211.0%
5Y+155.0%
10Y-7.0%
12.18%
Return on Invested Capital
2%
3Y-198.0%
5Y-1731.0%
10Y+40.0%
ILMN

Illumina, Inc. Cash Conversion Engine

ILMN ยท NASDAQ
Net Income850.00M
Depreciation & Amortization270.00M
Stock-Based Compensation0.00
Change in Working Capital-153.00M
Others-7.00M
Capital Expenditures-148.00M
Free Cash Flow931.00M

Cash Flow Quality Analysis

FCF Conversion Rate

109.5%

Excellent cash generation. The company converts earnings to cash at or above 100%, indicating high-quality earnings.

CapEx Intensity

13.7%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

+31.3%

Strong FCF growth demonstrates improving cash generation and business momentum. Positive signal for sustainability.

Working Capital Impact

-$153.00M

Minimal working capital impact on FCF. Changes in operating assets and liabilities well-managed.

Cash Flow Quality Insight

Exceptional cash generation: High-quality earnings converting to growing free cash flow. The company demonstrates strong pricing power, efficient operations, and disciplined capital allocation.

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Illumina, Inc. Funding & Solvency Profile

ILMN ยท NASDAQ
Cash & Cash Equivalents1.09B
Net Receivables738.00M
Inventory611.00M
Other Current Assets234.00M
Total Current Assets3 B
Property, Plant & Equipment1.13B
Goodwill & Intangible Assets1.71B
Long-Term Investments0.00
Other Non-Current Assets523.00M
Total Non-Current Assets2 B
Total Assets
6.56B

Financial Health Analysis

Current Ratio

1.75x

Strong liquidity. The company has adequate resources to meet short-term liabilities.

Debt-to-Equity Ratio

1.17x

Elevated leverage. Debt exceeds equity, which amplifies both gains and risks. Monitor debt servicing ability.

Working Capital

1 B

Strong working capital position provides significant operational flexibility and financial cushion.

Asset Composition

42% Current

Balanced asset mix between current and non-current assets, typical of many stable businesses.

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Illumina, Inc. Street Expectations Map

ILMN ยท NASDAQ

Wall Street analysts project that ILMN stock may decline over the coming 12 months. The consensus 1-year price target stands at 151.40, with estimates ranging from a low of 122.00 to a high of 180.00.

Lowest Target
122.00
-28.63%
Consensus Target
151.40
-11.43%
Highest Target
180.00
5.31%

The consensus 1-year price target stands at 151.40, with estimates ranging from a low of 122.00 to a high of 180.00.

Analyst Consensus Analysis

Upside Potential

-11.4%

Downside risk. Current price above analyst targets indicates potential overvaluation. Exercise caution and review catalysts.

Analyst Agreement

38.3% spread

Good consensus alignment. Moderate target spread reflects general agreement on value drivers with some variance in assumptions.

Risk-Reward Profile

0.19x

Unfavorable risk-reward. Downside risk exceeds upside potential. Consider defensive positioning or alternative opportunities.

Analyst Conviction

Low

Bearish or uncertain outlook. Limited upside or poor consensus suggests challenges ahead or fundamental concerns.

Market Sentiment Insight

Monitor and evaluate: Current analyst consensus suggests limited conviction or near-term catalysts. Stay informed on company developments and reassess positioning as new information emerges.

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Illumina, Inc. Insider Positioning

ILMN ยท NASDAQ

During the last 12 months, insiders have purchased $85K and sold $29.71M worth of ILMN shares, resulting in $29.63M of net selling activity.

3 Months

Bought

0

0.00

Sold

197.9K

29.17M

Net Activity

-29.2M

-$29.17M

3-6 Months

Bought

200

23.56K

Sold

4.6K

545.49K

Net Activity

-522K

-$522K

6-9 Months

Bought

500

61.06K

Sold

0

0.00

Net Activity

+61K

+$61K

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
GS

Gottlieb Scott

Director

700 sharesโ€ข2 transactions

$85K

Top Sellers

1
MKA

Meister Keith A.

Director

197.2K sharesโ€ข2 transactions

$29.07M

2
LP

Leckman Patricia

Officer: Svp, Chief People Officer

2.4K sharesโ€ข1 transactions

$275K

3
DSM

Davies Scott M

Officer: Chief Legal Officer

1.7K sharesโ€ข2 transactions

$199K

4
WCJ

Wedel Christensen Jakob

Officer: Svp, Strategy/Corp Development

1.2K sharesโ€ข2 transactions

$168K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $29.63M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$29.17M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

4 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

0.00%
Dividend Yield
3Y-
5Y-
10Y-100.0%
ย 

ilmn Dividend History

ILMN
10Y CAGR +0%
Latest $0
Annual $0
Stable dividend payments
Last Period: +0%