Humacyte, Inc.

Humacyte, Inc.

HUMA·NASDAQ

$1.48

+6.5%
HealthcareBiotechnology

Humacyte, Inc. engages in the development and manufacture of off-the-shelf, implantable, and bioengineered human tissues for the treatment of diseases and conditions across a range of anatomic locations in multiple therapeutic areas. The company using its proprietary and scientific technology platform to engineer and manufacture human acellular vessels (HAVs). Its investigational HAVs are designed to be easily implanted into any patient without inducing a foreign body response or leading to immune rejection. The company is developing a portfolio of HAVs, which would target the vascular repair, reconstruction, and replacement market, including vascular trauma; arteriovenous access for hemodialysis; peripheral arterial disease; and coronary artery bypass grafting, as well as developing its HAVs for pediatric heart surgery and cellular therapy delivery, including pancreatic islet cell transplantation to treat Type 1 diabetes. The company was founded in 2004 and is headquartered in Durham, North Carolina.

At a Glance

Live Snapshot
Market Cap$248.64M
EPS-0.2600
P/E Ratio-5.69
Earnings Date08/10/2026
-106.99%
Return on Invested Capital
13%
3Y+147.0%
5Y+65.0%
10Y+101.0%
-1313.38%
Return on Equity
-565%
3Y+12735.0%
5Y+1295.0%
10Y+1933.0%
-35.09%
Return on Assets
-67%
3Y+499.0%
5Y-44.0%
10Y-31.0%
Humacyte, Inc.

Humacyte, Inc. Management Team

HUMA · NASDAQ
MW

Mr. William John Scheessele

Chief Commercial Officer

Born 1972(Age 54)
male
MD

Mr. Dale A. Sander

Chief Financial Officer, Chief Corporate Development Officer & Treasurer

Compensation

$704,189

Born 1960(Age 66)
male
DS

Dr. Shamik J. Parikh M.D.

Chief Medical Officer

Compensation

$514,719

Born 1973(Age 53)
DH

Dr. Heather Ledbetter Prichard Ph.D.

Chief Operating Officer

Compensation

$653,205

Born 1978(Age 48)
MS

Ms. Sabrina Osborne GPHR, SPHR

Chief People Officer

female
DY

Dr. Yang Cao M.D., Ph.D.

Chief Regulatory Officer

Born 1966(Age 60)
DL

Dr. Laura E. Niklason M.D., Ph.D.

Founder, President, Chief Executive Officer & Director

Compensation

$905,436

Born 1963(Age 63)
huma

Humacyte, Inc. Insider Positioning

HUMA · NASDAQ

During the last 12 months, insiders have purchased $1.99M and sold $7.55M worth of HUMA shares, resulting in $5.56M of net selling activity.

3 Months

Bought

67.8K

59.84K

Sold

91.8K

82.29K

Net Activity

-22K

-$22K

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

800.0K

1.93M

Sold

4.5M

7.47M

Net Activity

-5.5M

-$5.54M

Top Buyers

1
SK

Sebelius Kathleen

Director

136.8K shares2 transactions

$243K

2
CMT

Constantino Michael T.

Director

91.0K shares2 transactions

$203K

3
WSR

Windham-Bannister Susan Richards

Director

80.0K shares1 transactions

$193K

4
GCB

Green Charles Bruce

Director

80.0K shares1 transactions

$193K

5
BJP

Bamforth John Philip

Director

80.0K shares1 transactions

$193K

Top Sellers

1
DBW

Dougan Brady W

Director

2.2M shares3 transactions

$3.73M

2
NLE

Niklason Laura E

Director, Officer: President, Ceo And Director

2.2M shares3 transactions

$3.73M

3
PSJ

Parikh Shamik J

Officer: Chief Medical Officer

45.9K shares1 transactions

$41K

4
SDA

Sander Dale A.

Officer: Cfo And Chief Corp. Dev. Off

45.9K shares1 transactions

$41K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $5.56M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.26:1

Weak buy/sell ratio. Selling significantly exceeds buying—monitor for potential fundamental concerns.

Recent Trend (3 Months)

$22K

Negative recent trend with net selling. Insiders have reduced positions in recent months, which could signal caution.

Insider Participation

Moderate Buying

5 insider buyers vs. 4 sellers. More insiders buying than selling indicates positive sentiment.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

HUMA - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 28, 2026
April 28, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 29, 2025
June 10, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 29, 2024
June 11, 2024
2024
DEF 14A

DEF 14A 2023

N/A

April 28, 2023
June 07, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 29, 2022
June 09, 2022
2022
Showing 1 to 5 of 5 filings