Halozyme Therapeutics, Inc.

Halozyme Therapeutics, Inc.

HALOยทNASDAQ

$69.82

+2.3%
HealthcareBiotechnology

Halozyme Therapeutics, Inc. operates as a biopharma technology platform company in the United States, Switzerland, Ireland, Belgium, Japan, and internationally. The company's products are based on the ENHANZE drug delivery technology, a patented recombinant human hyaluronidase enzyme (rHuPH20) that enables the subcutaneous delivery of injectable biologics, such as monoclonal antibodies and other therapeutic molecules, as well as small molecules and fluids. Its flagship product is Hylenex recombinant, a formulation of rHuPH20 to facilitate subcutaneous fluid administration for achieving hydration to enhance the dispersion and absorption of other injected drugs in subcutaneous urography and to improve resorption of radiopaque agents. The company also develops Perjeta; RITUXAN HYCELA and MabThera SC for the treatment of non-Hodgkin lymphoma and chronic lymphocytic leukemia (CLL); RITUXAN SC for patients with CLL; and HYQVIA for the treatment of immunodeficiency disorders. In addition, it is developing Tecentriq for non-small cell lung cancer; OCREVUS for multiple sclerosis; DARZALEX for the treatment of patients with amyloidosis, smoldering myeloma, and multiple myeloma; nivolumab for the treatment of solid tumors; ARGX-113, a human neonatal Fc receptor; ARGX-117 to treat autoimmune diseases; and BMS-986179, an anti-CD-73 antibody. The company has collaborations with F. Hoffmann-La Roche, Ltd.; Hoffmann-La Roche, Inc.; Baxalta US Inc.; Baxalta GmbH; Pfizer Inc.; Janssen Biotech, Inc.; AbbVie, Inc.; Eli Lilly and Company; Bristol-Myers Squibb Company; Alexion Pharma Holding; ARGENX BVBA; Horizon Therapeutics plc; National Institute of Allergy and Infectious Diseases; Centre for the AIDS Programme of Research in South Africa; and ViiV Healthcare Limited for small and large molecule targets for the treatment and prevention of HIV. Halozyme Therapeutics, Inc. was founded in 1998 and is based in San Diego, California.

At a Glance

Live Snapshot
Market Cap$8.28B
EPS2.6400
P/E Ratio26.45
Earnings Date08/04/2026

Intrinsic Alpha Methodology

Thesis Lenses

Signal ยท Driver ยท Risk

Signal

High confidence

Valuation multiple is elevated (P/E 26.4).

Valuation inputs: P/E 26.4, earnings yield +3.8%, momentum +2.3%.

If multiples stay elevated while momentum fades, downside repricing risk rises.

Driver

High confidence

Return profile is strong (ROE +6.5%, ROIC +23.6%).

Profitability stack: net margin +22.7%, ROE +6.5%, ROIC +23.6%.

Quality deterioration often appears in margins before it shows up in headline EPS.

Risk

High confidence

Risk profile is balanced but has notable pressure points to monitor.

Risk factors: liabilities/assets +98.1%, momentum +2.3%, net margin +22.7%.

Higher leverage with weak momentum and thin margins can amplify drawdown severity.

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Halozyme Therapeutics, Inc. Market vs Earnings Trajectory

HALO ยท NASDAQ

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Halozyme Therapeutics, Inc.

Halozyme Therapeutics, Inc. Fair Value Envelope

HALO ยท NASDAQ

Our analysis suggests that HALO has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $69.82, this represents a potential HIDDEN relative to our calculated worth for Halozyme Therapeutics, Inc..

Intrinsic Value
Current Price: $69.82
3Y+78.0%
5Y+178.0%
10Y-426.0%
3Y+112.0%
5Y+422.0%
10Y+852.0%
3Y+57.0%
5Y+145.0%
10Y-408.0%
3Y+171.0%
5Y+1075.0%
10Y-1393.0%
3Y+174.0%
5Y+1117.0%
10Y-1304.0%
3Y+37.0%
5Y+335.0%
10Y+866.0%
Halozyme Therapeutics, Inc.

Halozyme Therapeutics, Inc. Profit Bridge

HALO ยท NASDAQ
Revenue1.40B
Cost of Goods Sold (305.44M)
Gross Profit1.09B
Operating Expenses (274.88M)
Operating Income816.29M
Interest Expense (18.13M)
Other Income/Expense-349.42M
Pretax Income466.88M
Income Tax (149.99M)
Net Income316.89M
Net Income
316.89M

Profitability Analysis

Gross Margin

78.1%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

58.4%

Outstanding operational efficiency. The company generates substantial profit from core operations.

Net Profit Margin

22.7%

Exceptional profitability. The company converts a significant portion of revenue to bottom-line earnings.

Effective Tax Rate

32.1%

Higher tax burden may reflect limited tax optimization or operations in high-tax jurisdictions.

Profitability Insight

Exceptional profitability across all levels: Strong pricing power, efficient operations, and healthy bottom line indicate a high-quality business with sustainable competitive advantages.

78.13%
Gross Profit Margin
-7%
3Y-1.0%
5Y-7.0%
10Y+1.0%
58.45%
Operating Profit Margin
8%
3Y+44.0%
5Y+8.0%
10Y-203.0%
22.69%
Net Profit Margin
-48%
3Y-26.0%
5Y-53.0%
10Y-132.0%
649.18%
Return on Equity
432%
3Y+445.0%
5Y+660.0%
10Y+105.0%
12.55%
Return on Assets
-42%
3Y+14.0%
5Y-44.0%
10Y-132.0%
23.59%
Return on Invested Capital
3%
3Y+87.0%
5Y-9.0%
10Y-163.0%
HALO

Halozyme Therapeutics, Inc. Cash Conversion Engine

HALO ยท NASDAQ
Net Income316.89M
Depreciation & Amortization88.05M
Stock-Based Compensation51.56M
Change in Working Capital-152.26M
Others346.68M
Capital Expenditures-6.97M
Free Cash Flow644.59M

Cash Flow Quality Analysis

FCF Conversion Rate

203.4%

Excellent cash generation. The company converts earnings to cash at or above 100%, indicating high-quality earnings.

CapEx Intensity

1.1%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

+37.6%

Strong FCF growth demonstrates improving cash generation and business momentum. Positive signal for sustainability.

Working Capital Impact

-$152.26M

Moderate working capital outflow. Typical for growing businesses, but ensure it's supporting revenue growth, not inefficiency.

Cash Flow Quality Insight

Exceptional cash generation: High-quality earnings converting to growing free cash flow. The company demonstrates strong pricing power, efficient operations, and disciplined capital allocation.

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Halozyme Therapeutics, Inc. Funding & Solvency Profile

HALO ยท NASDAQ
Cash & Cash Equivalents309.75M
Net Receivables457.99M
Inventory155.47M
Other Current Assets70.96M
Total Current Assets1 B
Property, Plant & Equipment82.23M
Goodwill & Intangible Assets1.53B
Long-Term Investments0.00
Other Non-Current Assets53.17M
Total Non-Current Assets135 M
Total Assets
2.67B

Financial Health Analysis

Current Ratio

2.76x

Excellent liquidity position. The company can easily cover its short-term obligations with substantial cushion.

Debt-to-Equity Ratio

11.17x

High financial leverage. Heavy reliance on debt may indicate increased financial risk and potential solvency concerns.

Working Capital

640 M

Strong working capital position provides significant operational flexibility and financial cushion.

Asset Composition

38% Current

Capital-intensive business with significant long-term investments in property, equipment, or intangibles.

Financial Health Insight

Mixed signals: Strong short-term liquidity provides comfort, but high overall leverage requires careful monitoring of debt servicing capabilities and refinancing risk.

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Halozyme Therapeutics, Inc. Street Expectations Map

HALO ยท NASDAQ

Wall Street analysts project that HALO stock may experience modest gains over the coming 12 months. The consensus 1-year price target stands at 75.00, with estimates ranging from a low of 56.00 to a high of 95.00.

Lowest Target
56.00
-19.79%
Consensus Target
75.00
7.42%
Highest Target
95.00
36.06%

The consensus 1-year price target stands at 75.00, with estimates ranging from a low of 56.00 to a high of 95.00.

Analyst Consensus Analysis

Upside Potential

+7.4%

Moderate upside. Analysts expect positive returns but with limited margin of safety. Consider entry timing.

Analyst Agreement

52.0% spread

Mixed analyst views. Wide target range suggests differing opinions on key value drivers, growth prospects, or risk factors.

Risk-Reward Profile

1.82x

Balanced risk-reward. Upside and downside potential relatively symmetric. Suitable for moderate risk tolerance with conviction in thesis.

Analyst Conviction

Low

Bearish or uncertain outlook. Limited upside or poor consensus suggests challenges ahead or fundamental concerns.

Market Sentiment Insight

Monitor and evaluate: Current analyst consensus suggests limited conviction or near-term catalysts. Stay informed on company developments and reassess positioning as new information emerges.

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Halozyme Therapeutics, Inc. Insider Positioning

HALO ยท NASDAQ

During the last 12 months, insiders have sold $17.57M worth of HALO shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

62.0K

4.06M

Net Activity

-4.1M

-$4.06M

3-6 Months

Bought

0

0.00

Sold

39.4K

2.82M

Net Activity

-2.8M

-$2.82M

6-9 Months

Bought

0

0.00

Sold

52.8K

3.79M

Net Activity

-3.8M

-$3.79M

9-12 Months

Bought

0

0.00

Sold

118.3K

6.91M

Net Activity

-6.9M

-$6.91M

Top Buyers

No buying activity

Top Sellers

1
TH

Torley Helen

Director, Officer: President And Ceo

227.2K sharesโ€ข28 transactions

$14.40M

2
CC

Caudill Cortney

Officer: Svp, Chief Operating Officer

22.2K sharesโ€ข2 transactions

$1.49M

3
LN

Labrosse Nicole

Officer: Svp, Chief Financial Officer

13.6K sharesโ€ข2 transactions

$1.03M

4
CB

Connaughton Bernadette

Director

9.5K sharesโ€ข7 transactions

$654K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $17.57M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$4.06M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

4 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

0.00%
Dividend Yield
3Y-
5Y-
10Y-
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halo Dividend History

HALO
10Y CAGR +0%
Latest $0
Annual $0
Stable dividend payments
Last Period: +0%