Structure Therapeutics Inc.

Structure Therapeutics Inc.

GPCR·NASDAQ

$37.50

-2.7%
HealthcareBiotechnology

Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral therapeutics to treat a range of chronic diseases with unmet medical needs. Its lead product candidate is GSBR-1290, an oral and biased small molecule agonist of glucagon-like-peptide-1 receptor, a validated G-protein-coupled receptors (GPCRs) drug target for type-2 diabetes mellitus and obesity. The company is also developing oral small molecule therapeutics targeting other GPCRs for the treatment of pulmonary and cardiovascular diseases, including ANPA-0073, a biased agonist, targeting apelin receptor, a GPCR that has been implicated in idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension; and LTSE-2578, an investigational oral small molecule lysophosphatidic acid 1 receptor antagonist for the treatment of IPF. The company was formerly known as ShouTi Inc. Structure Therapeutics Inc. was founded in 2016 and is headquartered in South San Francisco, California.

At a Glance

Live Snapshot
Market Cap$2.16B
EPS-2.4000
P/E Ratio-15.63
Earnings Date08/05/2026
gpcr

Structure Therapeutics Inc. Street Expectations Map

GPCR · NASDAQ

Wall Street analysts project that GPCR stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 114.75, with estimates ranging from a low of 90.00 to a high of 145.00.

Lowest Target
90.00
140.00%
Consensus Target
114.75
206.00%
Highest Target
145.00
286.67%

The consensus 1-year price target stands at 114.75, with estimates ranging from a low of 90.00 to a high of 145.00.

Analyst Consensus Analysis

Upside Potential

+206.0%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

47.9% spread

Mixed analyst views. Wide target range suggests differing opinions on key value drivers, growth prospects, or risk factors.

Analyst Conviction

Moderate

Neutral sentiment. Fair value pricing with moderate agreement suggests wait-and-see approach or catalyst-driven opportunity.

Market Sentiment Insight

Monitor and evaluate: Current analyst consensus suggests limited conviction or near-term catalysts. Stay informed on company developments and reassess positioning as new information emerges.

gpcr

Structure Therapeutics Inc. Forward Estimates of Revenue

GPCR · NASDAQ
Latest Revenue
0.00
FY 2025
Avg Estimate
31.25M
FY 2026
Estimate Range
31.25M - 31.25M
Analyst Spread

Forward Growth Analysis

Analyst Coverage9 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

gpcr

Structure Therapeutics Inc. Forward Estimates of Net Income

GPCR · NASDAQ
Latest Net Income
-141.20M
FY 2025
Avg Estimate
-25.67M
FY 2026
Estimate Range
-122.35M - 71.00M
Analyst Spread

Forward Growth Analysis

Projected Growth+81.8%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage9 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread753%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomes—suggests elevated risk and potential volatility.

gpcr

Structure Therapeutics Inc. Forward Estimates of EPS

GPCR · NASDAQ
Latest EPS
-2.40
FY 2025
Avg Estimate
$-1.38
FY 2026
Estimate Range
$-2.07 - $1.20
Analyst Spread

Forward Growth Analysis

Projected Growth+42.4%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage10 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread236%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomes—suggests elevated risk and potential volatility.

gpcr

Structure Therapeutics Inc. Forward Estimates of EBIT

GPCR · NASDAQ
Latest EBIT
-140.69M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage9 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

gpcr

Structure Therapeutics Inc. Forward Estimates of EBITDA

GPCR · NASDAQ
Latest EBITDA
-136.79M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage9 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

gpcr

Structure Therapeutics Inc. Forward Estimates of SG&A Expense

GPCR · NASDAQ
Latest SG&A Expense
61.55M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth-100.0%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage9 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

gpcr

Structure Therapeutics Inc. Insider Positioning

GPCR · NASDAQ

During the last 12 months, there has been no insider trading activity reported for GPCR.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

No buying activity

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Neutral

No insider trading activity reported. This could indicate blackout periods, lack of conviction, or regulatory restrictions.

Insider Participation

No Activity

No insider trading activity reported from any insiders in the past year.