FOLD - NASDAQ
Amicus Therapeutics, Inc.
$14.49
+0.0000%Amicus Therapeutics, Inc., a biotechnology company, focuses on discovering, developing, and delivering medicines for rare diseases. Its commercial product and product candidates include Galafold, an oral precision medicine for the treatment of adults with a confirmed diagnosis of Fabry disease and an amenable galactosidase alpha gene variant based on in vitro assay data. It also develops AT-GAA, a novel treatment paradigm for Pompe disease; enzyme replacement therapies for Pompe diseases; CLN3, which is in Phase 1/2 clinical study to evaluate the safety and efficacy of a single intrathecal administration of an AAV serotype AT-GTX-502 gene therapy in patients with CLN3; and CDKL5, a gene on the X-chromosome encoding the CDKL5 protein that regulates the expression of essential proteins for normal brain development. The company has collaboration and license agreements with Nationwide Children's Hospital; University of Pennsylvania; and GlaxoSmithKline. Amicus Therapeutics, Inc. was incorporated in 2002 and is headquartered in Philadelphia, Pennsylvania.
At a Glance
Live SnapshotAmicus Therapeutics, Inc. Profit Bridge
Profitability Analysis
Gross Margin
Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.
Operating Margin
Acceptable margins but limited operational leverage. Operating expense control is important.
Net Profit Margin
Net losses indicate the company is burning cash. Sustainability depends on path to profitability.
Effective Tax Rate
Higher tax burden may reflect limited tax optimization or operations in high-tax jurisdictions.
Profitability Insight
Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.
Amicus Therapeutics, Inc. Income Statement
FOLD • NASDAQ
| Amicus Therapeutics, Inc. Income Statement | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 | Dec 2020 | Dec 2019 | Dec 2018 | Dec 2017 | Dec 2016 | Dec 2015 | Dec 2014 | Dec 2013 | Dec 2012 | Dec 2011 | Dec 2010 | Dec 2009 | Dec 2008 | Dec 2007 | Dec 2006 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
REVENUE | ||||||||||||||||||||
634.2M | 528.3M | 399.4M | 329.2M | 305.5M | 260.9M | 182.2M | 91.2M | 36.9M | 5M | 0.0 | 1.2M | 363K | 18.4M | 21.4M | 922K | 64.4M | 15M | 1.8M | 0.0 | |
GROSS PROFIT | ||||||||||||||||||||
(80.4M) | (52.9M) | (37.3M) | (38.6M) | (34.5M) | (31M) | (22M) | (14.4M) | (6.2M) | (833K) | (1.8M) | (0.0) | (13.5M) | (20.4M) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | |
553.8M | 475.4M | 362M | 290.6M | 271M | 229.8M | 160.3M | 76.8M | 30.7M | 4.1M | -1.8M | 1.2M | -13.1M | -2M | 21.4M | 922K | 64.4M | 15M | 1.8M | 0.0 | |
OPERATING INCOME | ||||||||||||||||||||
(519.3M) | (450.5M) | (439.2M) | (502.8M) | (477.5M) | (476.8M) | (464.3M) | (402.3M) | (241.6M) | (179.2M) | (126M) | (69.9M) | (62.6M) | (71.3M) | (72.3M) | (56.8M) | (70.2M) | (58.9M) | (47.6M) | (46.9M) | |
(383.5M) | (323.4M) | (275.3M) | (213M) | (192.7M) | (156.4M) | (169.9M) | (127.2M) | (88.7M) | (71.2M) | (47.3M) | (20.7M) | (18.9M) | (19.4M) | (19.9M) | (15.7M) | (20M) | (19.7M) | (15.3M) | (12.3M) | |
(135.8M) | (109.4M) | (152.4M) | (276.7M) | (272M) | (308.4M) | (286.4M) | (270.9M) | (149.3M) | (104.8M) | (76.9M) | (47.6M) | (41.9M) | (50.3M) | (50.9M) | (39M) | (48.1M) | (37.8M) | (31.1M) | (33.6M) | |
34.5M | 24.9M | -77.2M | -212.1M | -206.4M | -247M | -304M | -328.8M | -442M | -181.9M | -130.4M | -68.7M | -64.2M | -52.9M | -50.9M | -55.8M | -7.4M | -44M | -45.8M | -46.9M | |
PRE-TAX INCOME | ||||||||||||||||||||
(46.2M) | (49.6M) | (50.1M) | (37.1M) | (32.5M) | (22.4M) | (18.9M) | (22.4M) | (17.2M) | (5.4M) | (1.6M) | (1.5M) | (46K) | (89K) | (148K) | (260K) | (278K) | (218K) | (0.0) | (0.0) | |
-42.8M | -44.2M | -43.1M | -34.1M | -32M | -19.2M | -8.6M | -11.9M | -13.1M | -3.8M | -649K | -1.3M | 128K | 227K | 12K | -104K | 719K | 4.6M | 0.0 | 0.0 | |
(0.0) | (17.7M) | (11.6M) | (13M) | (12.7M) | (12M) | (8.1M) | -5.6M | (6M) | -4.8M | -80K | -77K | (1.7M) | (21K) | (1.6M) | (2.1M) | (2.1M) | (1.5M) | (1.2M) | (0.0) | |
-34.3M | -53.6M | -72.9M | -29.9M | -35.1M | -27.3M | -51.9M | -23.6M | -7.1M | -21.9M | -6.1M | -1.3M | 1M | 901K | 2.8M | -237K | 783K | 4.6M | 4.6M | 514.4K | |
191K | -28.8M | -150.1M | -242M | -241.6M | -274.3M | -355.9M | -349.1M | -449.1M | -203.8M | -132.1M | -70M | -63.1M | -52M | -48M | -56.1M | -6.6M | -39.4M | -41.2M | -46.3M | |
NET INCOME | ||||||||||||||||||||
(27.3M) | (27.4M) | (1.5M) | -5.5M | (8.9M) | (2.6M) | (478K) | -94K | -165.1M | -3.7M | (1.5M) | -1.1M | -3.5M | -3.2M | -3.6M | -1.1M | (0.0) | (0.0) | (351K) | (0.0) | |
-27.1M | -56.1M | -151.6M | -236.6M | -250.5M | -276.9M | -356.4M | -349M | -284M | -200M | -132.1M | -68.9M | -59.6M | -48.8M | -44.4M | -54.9M | -6.6M | -39.4M | -41.2M | -46.3M |
SEC Filings
FOLD - Filing history and reports
| Filing Type | Filing Date | Period Ending | Fiscal Year | Actions |
|---|---|---|---|---|
8-K 8-K 2026 N/A | April 27, 2026 | April 27, 2026 | 2026 | |
8-K 8-K 2026 N/A | April 23, 2026 | April 23, 2026 | 2026 | |
8-K 8-K 2026 N/A | March 03, 2026 | March 03, 2026 | 2026 | |
8-K 8-K 2026 N/A | February 20, 2026 | February 20, 2026 | 2026 | |
10-K 10-K 2025 FY FY | February 20, 2026 | December 31, 2025 | 2025 | |
8-K 8-K 2026 N/A | January 26, 2026 | January 26, 2026 | 2026 | |
8-K 8-K 2025 N/A | December 19, 2025 | December 19, 2025 | 2025 | |
10-Q 10-Q 2025 Q3 Q3 | November 04, 2025 | September 30, 2025 | 2025 | |
8-K 8-K 2025 N/A | November 04, 2025 | November 04, 2025 | 2025 | |
8-K 8-K 2025 N/A | July 31, 2025 | July 31, 2025 | 2025 |
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