89bio, Inc.

89bio, Inc.

ETNB·NASDAQ

$14.84

+0.0000%
HealthcareBiotechnology

89bio, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapies for the treatment of liver and cardio-metabolic diseases. Its lead product candidate is pegozafermin, a glycoPEGylated analog of fibroblast growth factor 21 for the treatment of nonalcoholic steatohepatitis. The company also intends to develop pegozafermin for the treatment of severe hypertriglyceridemia. 89bio, Inc. was incorporated in 2018 and is headquartered in San Francisco, California.

At a Glance

Live Snapshot
Market Cap$2.20B
EPS-3.5100
P/E Ratio-2.23
Earnings Date11/06/2025
etnb

89bio, Inc. Street Expectations Map

ETNB · NASDAQ

Wall Street analysts project that ETNB stock may see slight declines over the coming 12 months. The consensus 1-year price target stands at 14.50, with estimates ranging from a low of 14.50 to a high of 14.50.

Lowest Target
14.50
-2.29%
Consensus Target
14.50
-2.29%
Highest Target
14.50
-2.29%

The consensus 1-year price target stands at 14.50, with estimates ranging from a low of 14.50 to a high of 14.50.

Analyst Consensus Analysis

Upside Potential

-2.3%

Fair value territory. Stock trading near consensus target suggests limited near-term catalysts. Focus on fundamental developments.

Analyst Agreement

0.0% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Risk-Reward Profile

1.00x

Balanced risk-reward. Upside and downside potential relatively symmetric. Suitable for moderate risk tolerance with conviction in thesis.

Analyst Conviction

Moderate

Neutral sentiment. Fair value pricing with moderate agreement suggests wait-and-see approach or catalyst-driven opportunity.

Market Sentiment Insight

Efficient pricing: Stock trading at fair value with strong consensus suggests market has priced in expectations. Look for fundamental inflection points or new catalysts to drive meaningful moves.

etnb

89bio, Inc. Forward Estimates of Revenue

ETNB · NASDAQ
Latest Revenue
0.00
FY 2024
Avg Estimate
2.92M
FY 2025
Estimate Range
2.92M - 2.92M
Analyst Spread

Forward Growth Analysis

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

etnb

89bio, Inc. Forward Estimates of Net Income

ETNB · NASDAQ
Latest Net Income
-367.08M
FY 2024
Avg Estimate
-233.18M
FY 2025
Estimate Range
-242.47M - -223.90M
Analyst Spread

Forward Growth Analysis

Projected Growth+36.5%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread8%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

etnb

89bio, Inc. Forward Estimates of EPS

ETNB · NASDAQ
Latest EPS
-3.51
FY 2024
Avg Estimate
$-2.21
FY 2025
Estimate Range
$-2.32 - $-2.14
Analyst Spread

Forward Growth Analysis

Projected Growth+37.1%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread8%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

etnb

89bio, Inc. Forward Estimates of EBIT

ETNB · NASDAQ
Latest EBIT
-371.68M
FY 2024
Avg Estimate
0.00
FY 2025
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

etnb

89bio, Inc. Forward Estimates of EBITDA

ETNB · NASDAQ
Latest EBITDA
-384.66M
FY 2024
Avg Estimate
0.00
FY 2025
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

etnb

89bio, Inc. Forward Estimates of SG&A Expense

ETNB · NASDAQ
Latest SG&A Expense
39.62M
FY 2024
Avg Estimate
0.00
FY 2025
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth-100.0%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

etnb

89bio, Inc. Insider Positioning

ETNB · NASDAQ

During the last 12 months, insiders have sold $4.98M worth of ETNB shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

335.4K

4.86M

Net Activity

-4.9M

-$4.86M

9-12 Months

Bought

0

0.00

Sold

10.5K

115.28K

Net Activity

-115K

-$115K

Top Buyers

No buying activity

Top Sellers

1
RCML

Ra Capital Management, L.P.

Director, 10 Percent Owner:

335.4K shares1 transactions

$4.86M

2
LQ

Le-Nguyen Quoc

Officer: See Remarks

10.5K shares1 transactions

$115K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $4.98M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Insider Participation

High Selling

2 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.