Dianthus Therapeutics, Inc.

Dianthus Therapeutics, Inc.

DNTHยทNASDAQ

$84.97

-1.5%
HealthcareBiotechnology

Dianthus Therapeutics, Inc. operates as a clinical-stage biotechnology company that designs, develops, and delivers novel monoclonal antibodies for people living with severe autoimmune and inflammatory diseases. It develops DNTH103 that is in phase 1 clinical trails in patients with generalized myasthenia gravis, multifocal motor neuropathy, and chronic inflammatory demyelinating polyneuropathy. Dianthus Therapeutics, Inc. was incorporated in 2015 and is based in New York, New York.

At a Glance

Live Snapshot
Market Cap$3.55B
EPS-4.2000
P/E Ratio-9.59
Earnings Date08/06/2026
dnth

Dianthus Therapeutics, Inc. Street Expectations Map

DNTH ยท NASDAQ

Wall Street analysts project that DNTH stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 111.91, with estimates ranging from a low of 55.00 to a high of 145.00.

Lowest Target
55.00
-35.27%
Consensus Target
111.91
31.71%
Highest Target
145.00
70.65%

The consensus 1-year price target stands at 111.91, with estimates ranging from a low of 55.00 to a high of 145.00.

Analyst Consensus Analysis

Upside Potential

+31.7%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

80.4% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Risk-Reward Profile

2.00x

Favorable risk-reward. Potential upside significantly exceeds downside risk, offering asymmetric return profile attractive for risk-tolerant investors.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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Dianthus Therapeutics, Inc. Forward Estimates of Revenue

DNTH ยท NASDAQ
Latest Revenue
2.04M
FY 2025
Avg Estimate
1.72M
FY 2026
Estimate Range
1.08M - 2.47M
Analyst Spread

Forward Growth Analysis

Projected Growth-15.8%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage9 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread81%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Dianthus Therapeutics, Inc. Forward Estimates of Net Income

DNTH ยท NASDAQ
Latest Net Income
-162.34M
FY 2025
Avg Estimate
-123.48M
FY 2026
Estimate Range
-148.24M - -98.72M
Analyst Spread

Forward Growth Analysis

Projected Growth+23.9%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage9 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread40%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Dianthus Therapeutics, Inc. Forward Estimates of EPS

DNTH ยท NASDAQ
Latest EPS
-4.20
FY 2025
Avg Estimate
$-3.67
FY 2026
Estimate Range
$-4.45 - $-2.96
Analyst Spread

Forward Growth Analysis

Projected Growth+12.6%

Solid growth trajectory indicates healthy business performance and competitive positioning.

Analyst Coverage9 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread40%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Dianthus Therapeutics, Inc. Forward Estimates of EBIT

DNTH ยท NASDAQ
Latest EBIT
-177.93M
FY 2025
Avg Estimate
-1.03M
FY 2026
Estimate Range
-1.48M - -650.43K
Analyst Spread

Forward Growth Analysis

Projected Growth+99.4%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage9 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread81%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Dianthus Therapeutics, Inc. Forward Estimates of EBITDA

DNTH ยท NASDAQ
Latest EBITDA
-177.93M
FY 2025
Avg Estimate
-1.03M
FY 2026
Estimate Range
-1.48M - -650.43K
Analyst Spread

Forward Growth Analysis

Projected Growth+99.4%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage9 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread81%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Dianthus Therapeutics, Inc. Forward Estimates of SG&A Expense

DNTH ยท NASDAQ
Latest SG&A Expense
34.33M
FY 2025
Avg Estimate
4.74M
FY 2026
Estimate Range
2.99M - 6.82M
Analyst Spread

Forward Growth Analysis

Projected Growth-86.2%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage9 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread81%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

dnth

Dianthus Therapeutics, Inc. Insider Positioning

DNTH ยท NASDAQ

During the last 12 months, insiders have purchased $9.44M and sold $8.89M worth of DNTH shares, resulting in $545K of net buying activity.

3 Months

Bought

0

0.00

Sold

86.7K

7.05M

Net Activity

-7.1M

-$7.05M

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

260.0K

9.44M

Sold

46.2K

1.84M

Net Activity

+7.6M

+$7.59M

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
GM

Garcia Marino

Director, Officer: Ceo And President

120.0K sharesโ€ข1 transactions

$4.72M

2
SR

Savitz Ryan

Officer: Cfo & Cbo

80.0K sharesโ€ข2 transactions

$2.44M

3
RS

Randhawa Simrat

Officer: Chief Medical Officer

60.0K sharesโ€ข1 transactions

$2.27M

Top Sellers

1
GM

Garcia Marino

Director, Officer: Ceo And President

43.5K sharesโ€ข1 transactions

$3.51M

2
SP

Soteropoulos Paula

Director

28.2K sharesโ€ข2 transactions

$2.20M

3
SR

Savitz Ryan

Officer: Evp, Cfo & Cbo

29.6K sharesโ€ข3 transactions

$1.75M

4
RS

Randhawa Simrat

Officer: Evp, Head Of R&D

31.6K sharesโ€ข2 transactions

$1.42M

Insider Activity Analysis

Net Insider Sentiment

Bullish

Moderately bullish with $545K net buying. Insiders show cautious optimism through measured share purchases.

Buy/Sell Ratio

1.06:1

Positive buy/sell ratio. Buying exceeds or matches selling, indicating net positive insider sentiment.

Recent Trend (3 Months)

$7.05M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

Moderate Selling

4 insider sellers vs. 3 buyers. More insiders selling than buying suggests cautious or negative sentiment.

Insider Activity Insight

Broad-based insider buying: When multiple insiders independently decide to purchase shares, it often reflects genuine confidence rather than coordinated optics. This pattern deserves attention, especially if buying followed a price decline.