Day One Biopharmaceuticals, Inc.

Day One Biopharmaceuticals, Inc.

DAWNยทNASDAQ

$21.53

+0.0000%
HealthcareBiotechnology

Day One Biopharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops and commercializes targeted therapies for patients with genetically defined cancers. Its lead product candidate is DAY101, an oral brain-penetrant type II pan-rapidly accelerated fibrosarcoma kinase inhibitor that is in Phase II clinical trial for pediatric patients with relapsed/progressive low-grade glioma. The company is also developing Pimasertib, an oral small molecule inhibitor of mitogen-activated protein kinase kinases 1 and 2. Day One Biopharmaceuticals, Inc. was incorporated in 2018 and is headquartered in South San Francisco, California.

At a Glance

Live Snapshot
Market Cap$2.22B
EPS-1.0400
P/E Ratio-20.70
Earnings Date05/13/2026
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Day One Biopharmaceuticals, Inc. Street Expectations Map

DAWN ยท NASDAQ

Wall Street analysts project that DAWN stock may see slight declines over the coming 12 months. The consensus 1-year price target stands at 21.50, with estimates ranging from a low of 21.50 to a high of 21.50.

Lowest Target
21.50
-0.14%
Consensus Target
21.50
-0.14%
Highest Target
21.50
-0.14%

The consensus 1-year price target stands at 21.50, with estimates ranging from a low of 21.50 to a high of 21.50.

Analyst Consensus Analysis

Upside Potential

-0.1%

Fair value territory. Stock trading near consensus target suggests limited near-term catalysts. Focus on fundamental developments.

Analyst Agreement

0.0% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Risk-Reward Profile

1.00x

Balanced risk-reward. Upside and downside potential relatively symmetric. Suitable for moderate risk tolerance with conviction in thesis.

Analyst Conviction

Moderate

Neutral sentiment. Fair value pricing with moderate agreement suggests wait-and-see approach or catalyst-driven opportunity.

Market Sentiment Insight

Efficient pricing: Stock trading at fair value with strong consensus suggests market has priced in expectations. Look for fundamental inflection points or new catalysts to drive meaningful moves.

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Day One Biopharmaceuticals, Inc. Forward Estimates of Revenue

DAWN ยท NASDAQ
Latest Revenue
158.18M
FY 2025
Avg Estimate
214.79M
FY 2026
Estimate Range
171.38M - 278.61M
Analyst Spread

Forward Growth Analysis

Projected Growth+35.8%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage8 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread50%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Day One Biopharmaceuticals, Inc. Forward Estimates of Net Income

DAWN ยท NASDAQ
Latest Net Income
-107.32M
FY 2025
Avg Estimate
-67.62M
FY 2026
Estimate Range
-159.89M - -6.12M
Analyst Spread

Forward Growth Analysis

Projected Growth+37.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage8 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread227%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Day One Biopharmaceuticals, Inc. Forward Estimates of EPS

DAWN ยท NASDAQ
Latest EPS
-1.04
FY 2025
Avg Estimate
$-0.67
FY 2026
Estimate Range
$-1.71 - $-0.07
Analyst Spread

Forward Growth Analysis

Projected Growth+35.4%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage7 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread244%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Day One Biopharmaceuticals, Inc. Forward Estimates of EBIT

DAWN ยท NASDAQ
Latest EBIT
-109.30M
FY 2025
Avg Estimate
142.90M
FY 2026
Estimate Range
114.01M - 185.35M
Analyst Spread

Forward Growth Analysis

Projected Growth+230.7%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage8 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread50%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Day One Biopharmaceuticals, Inc. Forward Estimates of EBITDA

DAWN ยท NASDAQ
Latest EBITDA
-105.82M
FY 2025
Avg Estimate
143.56M
FY 2026
Estimate Range
114.54M - 186.21M
Analyst Spread

Forward Growth Analysis

Projected Growth+235.7%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage8 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread50%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Day One Biopharmaceuticals, Inc. Forward Estimates of SG&A Expense

DAWN ยท NASDAQ
Latest SG&A Expense
120.59M
FY 2025
Avg Estimate
209.65M
FY 2026
Estimate Range
167.27M - 271.93M
Analyst Spread

Forward Growth Analysis

Projected Growth+73.9%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage8 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread50%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Day One Biopharmaceuticals, Inc. Insider Positioning

DAWN ยท NASDAQ

During the last 12 months, insiders have purchased $599K and sold $864K worth of DAWN shares, resulting in $265K of net selling activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

36.5K

422.98K

Net Activity

-423K

-$423K

6-9 Months

Bought

66.7K

599.27K

Sold

28.0K

249.62K

Net Activity

+350K

+$350K

9-12 Months

Bought

0

0.00

Sold

28.3K

191.47K

Net Activity

-191K

-$191K

Top Buyers

1
DHJ

Dable Habib J

Director

66.7K sharesโ€ข1 transactions

$599K

Top Sellers

1
BJ

Bender Jeremy

Director, Officer: Chief Executive Officer

47.4K sharesโ€ข3 transactions

$430K

2
DA

Dubow Adam

Officer: Gen Counsel & Secretary

15.1K sharesโ€ข3 transactions

$142K

3
YCNI

York Charles N Ii

Officer: Coo And Cfo

14.2K sharesโ€ข3 transactions

$134K

4
ML

Merendino Lauren

Officer: Chief Commercial Officer

13.3K sharesโ€ข3 transactions

$126K

5
VM

Vasconcelles Michael

Officer: Head Of Research And Dev.

2.7K sharesโ€ข1 transactions

$32K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Slightly bearish with $265K net selling. Selling modestly exceeds buying, which could be routine diversification rather than concern.

Buy/Sell Ratio

0.69:1

Moderately negative ratio. Selling is roughly double the buying, which may be routine or signal caution.

Insider Participation

High Selling

5 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.