Cytokinetics, Incorporated

Cytokinetics, Incorporated

CYTKยทNASDAQ

$70.71

+0.041%
HealthcareBiotechnology

Cytokinetics, Incorporated, a late-stage biopharmaceutical company, focuses on discovering, developing, and commercializing muscle activators and inhibitors as potential treatments for debilitating diseases. The company develops small molecule drug candidates primarily engineered to impact muscle function and contractility. Its drug candidates include omecamtiv mecarbil, a novel cardiac myosin activator that is in Phase III clinical trial in patients with heart failure; and reldesemtiv, a skeletal muscle troponin activator, which is in Phase III clinical trial to treat amyotrophic lateral sclerosis and spinal muscular atrophy. The company also develops CK-136, a novel cardiac troponin activator that is in Phase I clinical trial; aficamten, a novel cardiac myosin inhibitor, which is in Phase III clinical trial for the treatment of patients with symptomatic obstructive hypertrophic cardiomyopathy; and CK-3772271, a small molecule cardiac myosin inhibitor that is in Phase I clinical trial. Cytokinetics, Incorporated has a strategic alliance with Astellas Pharma Inc. The company was incorporated in 1997 and is headquartered in South San Francisco, California.

At a Glance

Live Snapshot
Market Cap$8.80B
EPS-6.5400
P/E Ratio-10.81
Earnings Date08/06/2026
-47.74%
Return on Invested Capital
12%
3Y+39.0%
5Y+157.0%
10Y-456.0%
119.00%
Return on Equity
-73%
3Y-67.0%
5Y-206.0%
10Y+582.0%
-55.10%
Return on Assets
31%
3Y+44.0%
5Y+131.0%
10Y-670.0%
Cytokinetics, Incorporated

Cytokinetics, Incorporated Management Team

CYTK ยท NASDAQ
MR

Mr. Robert I. Blum

Chief Executive Officer, President & Director

Compensation

$1,508,317

Born 1964(Age 62)
male
DJ

Dr. James A. Spudich Ph.D.

Co-Founder & Member of Scientific Advisory Board

Compensation

$21,938

Born 1942(Age 84)
MS

Mr. Sung H. Lee

EVice President & Chief Financial Officer

Compensation

$893,932

Born 1970(Age 56)
male
MA

Mr. Andrew M. Callos

Executive Vice President & Chief Commercial Officer

Compensation

$845,965

Born 1969(Age 57)
male
DF

Dr. Fady Ibraham Malik FACC, M.D., Ph.D.

Executive Vice President of Research & Development

Compensation

$909,769

Born 1964(Age 62)
MS

Mr. Scott R. Jordan

Senior Vice President of Global Marketing & Commercial Strategy

male
MS

Mr. Steven M. Cook J.D.

Senior Vice President of Global Supply Chain Operations & Technical Operations

Born 1959(Age 67)
male
MK

Ms. Kari K. Loeser J.D.

Vice President & Chief Compliance Officer

female
MH

Ms. Holly Laughlin

Vice President of Accounting & Corporate Controller

female
MM

Mr. Matt Yang

Vice President of Corporate Finance and Financial Planning & Analysis

male
MJ

Mr. Jeff Lotz

Vice President of Sales & Operations

male
cytk

Cytokinetics, Incorporated Insider Positioning

CYTK ยท NASDAQ

During the last 12 months, insiders have sold $30.72M worth of CYTK shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

195.7K

13.77M

Net Activity

-13.8M

-$13.77M

3-6 Months

Bought

0

0.00

Sold

77.7K

4.87M

Net Activity

-4.9M

-$4.87M

6-9 Months

Bought

0

0.00

Sold

154.3K

9.73M

Net Activity

-9.7M

-$9.73M

9-12 Months

Bought

0

0.00

Sold

61.2K

2.34M

Net Activity

-2.3M

-$2.34M

Top Buyers

No buying activity

Top Sellers

1
CA

Callos Andrew

Officer: Evp, Chief Commercial Officer

184.3K sharesโ€ข18 transactions

$11.80M

2
BRI

Blum Robert I

Director, Officer: President & Ceo

95.4K sharesโ€ข16 transactions

$5.37M

3
KEMM

Kaye Edward M. Md

Director

60.0K sharesโ€ข7 transactions

$3.66M

4
MFI

Malik Fady Ibraham

Officer: Evp Research & Development

43.9K sharesโ€ข18 transactions

$2.53M

5
LS

Lee Sung

Officer: Evp, Chief Financial Officer

28.8K sharesโ€ข2 transactions

$2.14M

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $30.72M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$13.77M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

CYTK - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 17, 2026
May 27, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 10, 2025
May 14, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 08, 2024
May 15, 2024
2024
DEF 14A

DEF 14A

N/A

April 07, 2023
April 07, 2023
ย 
DEF 14A

DEF 14A 2022

N/A

April 08, 2022
May 10, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 07, 2021
May 12, 2021
2021
DEF 14A

DEF 14A 2020

N/A

March 26, 2020
May 13, 2020
2020
DEF 14A

DEF 14A 2019

N/A

April 03, 2019
May 15, 2019
2019
DEF 14A

DEF 14A 2018

N/A

March 29, 2018
May 16, 2018
2018
DEF 14A

DEF 14A 2017

N/A

March 31, 2017
May 18, 2017
2017
Showing 1 to 10 of 22 filings