Coya Therapeutics, Inc.

Coya Therapeutics, Inc.

COYA·NASDAQ

$4.89

+5.4%
HealthcareBiotechnology

Coya Therapeutics, Inc., a clinical-stage biotechnology company, develops proprietary medicinal products to modulate the function of regulatory T cells (Tregs). The company's product candidate pipeline is based on therapeutic modalities, such as Treg-enhancing biologics, Treg-derived exosomes, and autologous Treg cell therapy. It is developing COYA 101, an autologous regulatory T-cell product candidate that has completed Phase 2a clinical trial for use in the treatment of Amyotrophic Lateral Sclerosis. The company's product candidates in IND-enabling studies include COYA 301, a Treg-enhancing biologic for use in the treatment of Frontotemporal Dementia; and COYA 302, a biologic combination for subcutaneous and/or intravenous administration intended to enhance Treg function while depleting T effector function and activated macrophages for use in the treatment of neurodegenerative and autoimmune diseases. It is also developing COYA 201, an allogeneic Treg exosome product candidate that is in preclinical stage for use in the treatment of neurodegenerative, autoimmune, and metabolic diseases; and COYA 206, an antigen directed Treg-derived exosome product candidate, which is in discovery stage. The company was incorporated in 2020 and is headquartered in Houston, Texas.

At a Glance

Live Snapshot
Market Cap$89.04M
EPS-1.2700
P/E Ratio-3.85
Earnings Date08/11/2026
3Y-
5Y-
10Y-
3Y+73.0%
5Y+1830.0%
10Y+1830.0%
3Y+48.0%
5Y+2645.0%
10Y+2645.0%
Coya Therapeutics, Inc.

Coya Therapeutics, Inc. Profit Bridge

COYA · NASDAQ
Revenue7.95M
Cost of Goods Sold (27.36K)
Gross Profit7.92M
Operating Expenses (28.18M)
Operating Income-20.27M
Interest Expense (0.00)
Other Income/Expense-957.39K
Pretax Income-21.22M
Income Tax (3.09K)
Net Income-21.23M
Net Income
-21.23M

Profitability Analysis

Gross Margin

99.7%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

-255.0%

Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.

Net Profit Margin

-267.1%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.

Coya Therapeutics, Inc. Income Statement

COYA • NASDAQ

Coya Therapeutics, Inc. Income StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
REVENUE
7.9M
3.6M
6M
0.0
0.0
0.0
GROSS PROFIT
(27.4K)
(11.9M)
(5.5M)
(4.4M)
(0.0)
(0.0)
7.9M
-8.3M
500.7K
-4.4M
0.0
0.0
OPERATING INCOME
(28.2M)
(8.9M)
(8.4M)
(5.4M)
(4.9M)
(1M)
(11.4M)
(8.9M)
(7.8M)
(4.8M)
(2.3M)
(668.7K)
(16.7M)
(11.9M)
(6M)
(4.9M)
(2.5M)
(373.5K)
-20.3M
-17.2M
-7.9M
-9.8M
-4.9M
-1M
PRE-TAX INCOME
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(39K)
0.0
0.0
0.0
0.0
0.0
-39K
(0.0)
-11.8M
-5.5M
-4.4M
(16.1K)
(0.0)
-957.4K
1.6M
639.4K
-2.4M
-21.5K
-57.6K
-21.2M
-15.6M
-7.3M
-12.2M
-4.9M
-1.1M
NET INCOME
(3.1K)
-720.3K
(723.9K)
(0.0)
(0.0)
(0.0)
-21.2M
-14.9M
-8M
-12.2M
-4.9M
-1.1M

SEC Filings

COYA - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

May 13, 2026
June 25, 2026
2026
8-K

8-K 2026

N/A

May 12, 2026
May 12, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 12, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 12, 2026
May 12, 2026
2026
8-K

8-K 2026

N/A

April 02, 2026
March 29, 2026
2026
S-3

S-3

N/A

March 16, 2026
March 16, 2026
 
10-K

10-K 2025 FY

FY

March 16, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 16, 2026
March 16, 2026
2026
8-K

8-K 2026

N/A

January 30, 2026
January 29, 2026
2026
8-K

8-K 2026

N/A

January 20, 2026
January 20, 2026
2026
Showing 1 to 10 of 77 filings