C4 Therapeutics, Inc.

C4 Therapeutics, Inc.

CCCCยทNASDAQ

$3.96

-8.8%
HealthcareBiotechnology

C4 Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel therapeutic candidates to degrade disease-causing proteins for the treatment of cancer, neurodegenerative conditions, and other diseases. Its lead product candidate is CFT7455, an orally bioavailable MonoDAC degrader of protein that is in Phase 1/2 trial targeting IKZF1 and IKZF3 for multiple myeloma and non-Hodgkin lymphomas, including peripheral T-cell lymphoma and mantle cell lymphoma. The company is also developing CFT8634, an orally bioavailable BiDAC degrader of BRD9, a protein target for synovial sarcoma and SMARCB1-deleted solid tumors; CFT1946, an orally bioavailable BiDAC degrader targeting V600X mutant BRAF to treat melanoma, non-small cell lung cancer (NSCLC), colorectal cancer, and other solid malignancies; CFT8919, an orally bioavailable, allosteric, and mutant-selective BiDAC degrader of epidermal growth factor receptor, or EGFR, with an L858R mutation in NSCLC; and earlier stage programs comprising RET degraders for the treatment of various cancers. C4 Therapeutics, Inc. has strategic collaborations with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc.; Biogen MA, Inc.; and Calico Life Sciences LLC. The company was incorporated in 2015 and is headquartered in Watertown, Massachusetts.

At a Glance

Live Snapshot
Market Cap$328.00M
EPS-1.2700
P/E Ratio-3.12
Earnings Date08/06/2026
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C4 Therapeutics, Inc. Street Expectations Map

CCCC ยท NASDAQ

Wall Street analysts project that CCCC stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 7.00, with estimates ranging from a low of 7.00 to a high of 7.00.

Lowest Target
7.00
76.77%
Consensus Target
7.00
76.77%
Highest Target
7.00
76.77%

The consensus 1-year price target stands at 7.00, with estimates ranging from a low of 7.00 to a high of 7.00.

Analyst Consensus Analysis

Upside Potential

+76.8%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

0.0% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Rare opportunity: Exceptional upside potential with strong analyst consensus creates a compelling setup. The combination of significant price target premium and tight agreement suggests high-conviction undervaluation that may attract institutional capital.

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C4 Therapeutics, Inc. Forward Estimates of Revenue

CCCC ยท NASDAQ
Latest Revenue
35.95M
FY 2025
Avg Estimate
22.84M
FY 2026
Estimate Range
16.49M - 27.44M
Analyst Spread

Forward Growth Analysis

Projected Growth-36.5%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread48%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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C4 Therapeutics, Inc. Forward Estimates of Net Income

CCCC ยท NASDAQ
Latest Net Income
-104.99M
FY 2025
Avg Estimate
-77.85M
FY 2026
Estimate Range
-81.00M - -74.70M
Analyst Spread

Forward Growth Analysis

Projected Growth+25.9%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread8%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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C4 Therapeutics, Inc. Forward Estimates of EPS

CCCC ยท NASDAQ
Latest EPS
-1.27
FY 2025
Avg Estimate
$-0.94
FY 2026
Estimate Range
$-0.98 - $-0.90
Analyst Spread

Forward Growth Analysis

Projected Growth+25.6%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread8%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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C4 Therapeutics, Inc. Forward Estimates of EBIT

CCCC ยท NASDAQ
Latest EBIT
-104.87M
FY 2025
Avg Estimate
-22.84M
FY 2026
Estimate Range
-27.44M - -16.49M
Analyst Spread

Forward Growth Analysis

Projected Growth+78.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread48%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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C4 Therapeutics, Inc. Forward Estimates of EBITDA

CCCC ยท NASDAQ
Latest EBITDA
-102.91M
FY 2025
Avg Estimate
-22.84M
FY 2026
Estimate Range
-27.44M - -16.49M
Analyst Spread

Forward Growth Analysis

Projected Growth+77.8%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread48%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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C4 Therapeutics, Inc. Forward Estimates of SG&A Expense

CCCC ยท NASDAQ
Latest SG&A Expense
36.20M
FY 2025
Avg Estimate
28.87M
FY 2026
Estimate Range
20.85M - 34.69M
Analyst Spread

Forward Growth Analysis

Projected Growth-20.2%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread48%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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C4 Therapeutics, Inc. Insider Positioning

CCCC ยท NASDAQ

During the last 12 months, insiders have purchased $461K and sold $46K worth of CCCC shares, resulting in $415K of net buying activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

10.0K

22.20K

Net Activity

-22K

-$22K

6-9 Months

Bought

12.1K

25.99K

Sold

2.8K

9.21K

Net Activity

+17K

+$17K

9-12 Months

Bought

301.2K

434.97K

Sold

7.4K

14.69K

Net Activity

+420K

+$420K

Top Buyers

1
GDR

Grogan Donna Roy

Director

51.8K sharesโ€ข3 transactions

$80K

2
AKC

Anderson Kenneth Carl

Director

48.5K sharesโ€ข3 transactions

$74K

3
CRHW

Cooper Ronald Harold Wilfred

Director

35.5K sharesโ€ข1 transactions

$51K

4
HSL

Hoerter Steven L.

Director

35.5K sharesโ€ข1 transactions

$51K

5
BL

Bessen Laura

Director

35.5K sharesโ€ข1 transactions

$51K

Top Sellers

1
RL

Reyno Leonard

Officer: Chief Medical Officer

17.4K sharesโ€ข2 transactions

$37K

2
AK

Adams Kendra

Officer: Chief Financial Officer

2.8K sharesโ€ข1 transactions

$9K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $415K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

10.00:1

Exceptional buy/sell ratio. Buying dramatically outweighs sellingโ€”one of the strongest possible insider signals.

Insider Participation

High Buying

5 insider buyers vs. 2 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.