Crescent Biopharma, Inc.

Crescent Biopharma, Inc.

CBIOยทNASDAQ

$17.95

+5.6%
HealthcareBiotechnology

Crescent Biopharma, Inc., an oncology company, develops therapies for cancer patients. Its pipeline includes a PD-1 x VEGF bispecific antibody, as well as novel antibody-drug conjugates to treat solid tumors. The company is headquartered in Waltham, Massachusetts.

At a Glance

Live Snapshot
Market Cap$495.05M
EPS-14.7800
P/E Ratio-1.21
Earnings Date07/30/2026
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Crescent Biopharma, Inc. Street Expectations Map

CBIO ยท NASDAQ

Wall Street analysts project that CBIO stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 33.00, with estimates ranging from a low of 29.00 to a high of 35.00.

Lowest Target
29.00
61.51%
Consensus Target
33.00
83.79%
Highest Target
35.00
94.93%

The consensus 1-year price target stands at 33.00, with estimates ranging from a low of 29.00 to a high of 35.00.

Analyst Consensus Analysis

Upside Potential

+83.8%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

18.2% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Rare opportunity: Exceptional upside potential with strong analyst consensus creates a compelling setup. The combination of significant price target premium and tight agreement suggests high-conviction undervaluation that may attract institutional capital.

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Crescent Biopharma, Inc. Forward Estimates of Revenue

CBIO ยท NASDAQ
Latest Revenue
10.84M
FY 2025
Avg Estimate
1.82M
FY 2026
Estimate Range
1.77M - 1.84M
Analyst Spread

Forward Growth Analysis

Projected Growth-83.2%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread4%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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Crescent Biopharma, Inc. Forward Estimates of Net Income

CBIO ยท NASDAQ
Latest Net Income
-153.94M
FY 2025
Avg Estimate
-36.30M
FY 2027
Estimate Range
-44.24M - -28.37M
Analyst Spread

Forward Growth Analysis

Projected Growth+76.4%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread44%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Crescent Biopharma, Inc. Forward Estimates of EPS

CBIO ยท NASDAQ
Latest EPS
-14.78
FY 2025
Avg Estimate
$-3.25
FY 2027
Estimate Range
$-4.25 - $-2.72
Analyst Spread

Forward Growth Analysis

Projected Growth+78.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread47%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Crescent Biopharma, Inc. Forward Estimates of EBIT

CBIO ยท NASDAQ
Latest EBIT
-149.76M
FY 2025
Avg Estimate
-1.09M
FY 2026
Estimate Range
-1.10M - -1.06M
Analyst Spread

Forward Growth Analysis

Projected Growth+99.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread4%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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Crescent Biopharma, Inc. Forward Estimates of EBITDA

CBIO ยท NASDAQ
Latest EBITDA
-149.67M
FY 2025
Avg Estimate
-1.09M
FY 2026
Estimate Range
-1.10M - -1.06M
Analyst Spread

Forward Growth Analysis

Projected Growth+99.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread4%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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Crescent Biopharma, Inc. Forward Estimates of SG&A Expense

CBIO ยท NASDAQ
Latest SG&A Expense
25.39M
FY 2025
Avg Estimate
799.56M
FY 2026
Estimate Range
776.28M - 807.33M
Analyst Spread

Forward Growth Analysis

Projected Growth+3049.1%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread4%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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Crescent Biopharma, Inc. Insider Positioning

CBIO ยท NASDAQ

During the last 12 months, insiders have purchased $20.80M worth of CBIO shares, with no selling activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

1.4M

18.24M

Sold

0

0.00

Net Activity

+18.2M

+$18.24M

9-12 Months

Bought

187.6K

2.56M

Sold

0

0.00

Net Activity

+2.6M

+$2.56M

Top Buyers

1
FFML

Fairmount Funds Management Llc

Director, 10 Percent Owner:

1.4M sharesโ€ข2 transactions

$18.38M

2
PJ

Pinkas Jan

Officer: Chief Scientific Officer

142.5K sharesโ€ข1 transactions

$1.87M

3
VJ

Violin Jonathan

Director

9.0K sharesโ€ข1 transactions

$138K

4
BA

Balcom Alexandra

Director

9.0K sharesโ€ข1 transactions

$138K

5
LDC

Lubner David Charles

Director

9.0K sharesโ€ข1 transactions

$138K

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $20.80M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

โˆž:1

Perfect buy/sell ratio. Only buying activity with zero sellingโ€”the most bullish possible insider signal.

Insider Participation

High Buying

5 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.