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CalciMedica, Inc.

CALCยทNASDAQ

$5.12

-1.9%
HealthcareBiotechnology

CalciMedica, Inc., a clinical-stage biotechnology company, focuses on developing therapies for life-threatening inflammatory diseases with unmet needs. Its proprietary technology targets the inhibition of calcium release-activated (CRAC) channels designs to modulate the immune response and protect against tissue cell injury in life-threatening inflammatory diseases. Its lead product candidate is Auxora, a proprietary intravenous-formulated CRAC channel inhibitor for the treatment of acute pancreatitis, asparaginase-associated acute pancreatitis, and acute kidney injury. The company is based in La Jolla, California.

At a Glance

Live Snapshot
Market Cap$73.78M
EPS-1.2200
P/E Ratio-2.91
Earnings Date03/26/2026

Intrinsic Alpha Methodology

Thesis Lenses

Signal ยท Driver ยท Risk

Signal

Medium confidence

Valuation multiple is compressed (P/E -2.9).

Valuation inputs: P/E -2.9, earnings yield N/A, momentum -1.9%.

If multiples stay elevated while momentum fades, downside repricing risk rises.

Driver

High confidence

Return profile is soft (ROE -95.1%, ROIC -1.5%).

Profitability stack: net margin 0.0%, ROE -95.1%, ROIC -1.5%.

Quality deterioration often appears in margins before it shows up in headline EPS.

Risk

High confidence

Risk profile is balanced but has notable pressure points to monitor.

Risk factors: liabilities/assets +27.2%, momentum -1.9%, net margin 0.0%.

Higher leverage with weak momentum and thin margins can amplify drawdown severity.

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CalciMedica, Inc. Market vs Earnings Trajectory

CALC ยท NASDAQ

Loading price and EPS data...

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CalciMedica, Inc. Fair Value Envelope

CALC ยท NASDAQ

Our analysis suggests that CALC has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $5.12, this represents a potential HIDDEN relative to our calculated worth for CalciMedica, Inc..

Intrinsic Value
Current Price: $5.12
3Y-95.0%
5Y-97.0%
10Y-96.0%

No Revenue Data

CALC has not reported any revenue values in the available annual periods.

3Y-62.0%
5Y-63.0%
10Y-52.0%
3Y-33.0%
5Y-32.0%
10Y-25.0%
3Y-34.0%
5Y-34.0%
10Y-29.0%
3Y-71.0%
5Y-51.0%
10Y+11.0%
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CalciMedica, Inc. Profit Bridge

CALC ยท NASDAQ
Revenue0.00
Cost of Goods Sold (0.00)
Gross Profit0.00
Operating Expenses (24.20M)
Operating Income-24.20M
Interest Expense (0.00)
Other Income/Expense10.50M
Pretax Income-13.70M
Income Tax (0.00)
Net Income-13.70M
Net Income
-13.70M

Profitability Analysis

No Gross Profit Margin Data

CALC has not reported any gross profit margin values in the available annual periods.

No Operating Profit Margin Data

CALC has not reported any operating profit margin values in the available annual periods.

No Net Profit Margin Data

CALC has not reported any net profit margin values in the available annual periods.

-95.07%
Return on Equity
-77%
3Y+73.0%
5Y-27.0%
10Y-60.0%
-69.21%
Return on Assets
-75%
3Y+33.0%
5Y-24.0%
10Y-57.0%
-150.24%
Return on Invested Capital
-68%
3Y+172.0%
5Y+14.0%
10Y-37.0%
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CalciMedica, Inc. Cash Conversion Engine

CALC ยท NASDAQ
Net Income-13.70M
Depreciation & Amortization58.00K
Stock-Based Compensation2.31M
Change in Working Capital-495.00K
Others-9.32M
Capital Expenditures-8.00K
Free Cash Flow-21.15M

Cash Flow Quality Analysis

FCF Conversion Rate

154.4%

Excellent cash generation. The company converts earnings to cash at or above 100%, indicating high-quality earnings.

CapEx Intensity

-0.0%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

+18.0%

Strong FCF growth demonstrates improving cash generation and business momentum. Positive signal for sustainability.

Working Capital Impact

-$495.00K

Minimal working capital impact on FCF. Changes in operating assets and liabilities well-managed.

Cash Flow Quality Insight

Exceptional cash generation: High-quality earnings converting to growing free cash flow. The company demonstrates strong pricing power, efficient operations, and disciplined capital allocation.

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CalciMedica, Inc. Funding & Solvency Profile

CALC ยท NASDAQ
Cash & Cash Equivalents5.47M
Net Receivables0.00
Inventory0.00
Other Current Assets539.00K
Total Current Assets15 M
Property, Plant & Equipment49.00K
Goodwill & Intangible Assets0.00
Long-Term Investments0.00
Other Non-Current Assets11.00K
Total Non-Current Assets60 K
Total Assets
14.91M

Financial Health Analysis

Current Ratio

4.04x

Excellent liquidity position. The company can easily cover its short-term obligations with substantial cushion.

Working Capital

11 M

Strong working capital position provides significant operational flexibility and financial cushion.

Asset Composition

100% Current

Asset-light business model with high liquidity. Majority of assets are easily convertible to cash.

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CalciMedica, Inc. Street Expectations Map

CALC ยท NASDAQ

Wall Street analysts project that CALC stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 266.00, with estimates ranging from a low of 14.00 to a high of 392.00.

Lowest Target
14.00
173.44%
Consensus Target
266.00
5095.31%
Highest Target
392.00
7556.25%

The consensus 1-year price target stands at 266.00, with estimates ranging from a low of 14.00 to a high of 392.00.

Analyst Consensus Analysis

Upside Potential

+5095.3%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

142.1% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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CalciMedica, Inc. Insider Positioning

CALC ยท NASDAQ

During the last 12 months, insiders have purchased $249K and sold $4K worth of CALC shares, resulting in $246K of net buying activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

13.2K

39.76K

Sold

0

0.00

Net Activity

+40K

+$40K

9-12 Months

Bought

85.2K

209.48K

Sold

1.0K

3.65K

Net Activity

+206K

+$206K

Top Buyers

1
REW

Roberts Eric W

Director, 10 Percent Owner, Officer: Chief Business Officer

70.9K sharesโ€ข19 transactions

$175K

2
HS

Hebbar Sudarshan

Officer: Chief Medical Officer

15.5K sharesโ€ข3 transactions

$43K

3
WRN

Wilson Robert N

Director

4.5K sharesโ€ข1 transactions

$13K

4
LAR

Leheny A. Rachel

Director, 10 Percent Owner, Officer: Chief Executive Officer

3.5K sharesโ€ข2 transactions

$10K

5
SKA

Stauderman Kenneth A.

Officer: Chief Scientific Officer

2.0K sharesโ€ข2 transactions

$6K

Top Sellers

1
SKA

Stauderman Kenneth A.

Officer: Chief Scientific Officer

1.0K sharesโ€ข1 transactions

$4K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $246K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

68.28:1

Exceptional buy/sell ratio. Buying dramatically outweighs sellingโ€”one of the strongest possible insider signals.

Insider Participation

High Buying

5 insider buyers vs. 1 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.

No Dividend Yield Data

CALC has not reported any dividend yield values in the available annual periods.

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calc Dividend History

CALC
10Y CAGR +0%
Latest $0
Annual $0
Stable dividend payments
Last Period: +0%