Aldeyra Therapeutics, Inc.

Aldeyra Therapeutics, Inc.

ALDXยทNASDAQ

$1.86

+0.71%
HealthcareBiotechnology

Aldeyra Therapeutics, Inc., a biotechnology company, develops and commercializes medicines for immune-mediated ocular and systemic diseases. The company's lead product candidate is reproxalap, a reactive aldehyde species (RASP)modulator, which is in Phase III clinical trial for the treatment of dry eye diseases and allergic conjunctivitis. It also develops ADX-629, a first-in-class orally administered RASP modulator that is Phase II clinical trial for psoriasis, asthma, and COVID-19; and ADX-2191, a dihydrofolate reductase inhibitor which is in phase 3 for the prevention of proliferative vitreoretinopathy, and phase II clinical trial for the treatment of retinitis pigmentosa, as well as for treating primary vitreoretinal lymphoma. The company has a license agreement with Madrigal Pharmaceuticals, Inc. for developing ADX-1612, which inhibits the protein chaperome for the treatment of inflammatory diseases. The company was formerly known as Aldexa Therapeutics, Inc. and changed its name to Aldeyra Therapeutics, Inc. in March 2014. Aldeyra Therapeutics, Inc. was incorporated in 2004 and is based in Lexington, Massachusetts.

At a Glance

Live Snapshot
Market Cap$112.20M
EPS-0.5600
P/E Ratio-3.32
Earnings Date07/31/2026
-58.99%
Return on Invested Capital
-15%
3Y+57.0%
5Y+29.0%
10Y-28.0%
-76.49%
Return on Equity
-3%
3Y+86.0%
5Y+21.0%
10Y-11.0%
-46.97%
Return on Assets
-12%
3Y+37.0%
5Y+4.0%
10Y-37.0%
Aldeyra Therapeutics, Inc.

Aldeyra Therapeutics, Inc. Management Team

ALDX ยท NASDAQ
DS

Dr. Stephen G. Machatha Ph.D.

Chief Development Officer

Compensation

$563,076

Born 1977(Age 49)
DT

Dr. Todd C. Brady M.D., Ph.D.

Chief Executive Officer, President & Director

Compensation

$930,828

Born 1972(Age 54)
MM

Mr. Michael Alfieri

Head of Finance and Principal Financial & Accounting Officer

Compensation

$111,650

Born 1965(Age 61)
male
DB

David Burke

Head of Investor Relations

LN

Laura Nichols

Operations Manager

aldx

Aldeyra Therapeutics, Inc. Insider Positioning

ALDX ยท NASDAQ

During the last 12 months, insiders have purchased $160K and sold $114K worth of ALDX shares, resulting in $46K of net buying activity.

3 Months

Bought

75.0K

105.10K

Sold

0

0.00

Net Activity

+105K

+$105K

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

17.9K

54.71K

Sold

22.1K

113.71K

Net Activity

-59K

-$59K

Top Buyers

1
DR

Douglas Richard

Director

71.7K sharesโ€ข2 transactions

$103K

2
AM

Alfieri Michael

Officer: Principal Financial Officer

7.5K sharesโ€ข2 transactions

$20K

3
PGM

Phillips Gary M.

Director

3.6K sharesโ€ข1 transactions

$10K

4
BB

Bronstein Ben

Director

3.6K sharesโ€ข1 transactions

$10K

5
WN

Walker Neal

Director

2.4K sharesโ€ข1 transactions

$6K

Top Sellers

1
MS

Machatha Stephen

Officer: Chief Development Officer

22.1K sharesโ€ข1 transactions

$114K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Moderately bullish with $46K net buying. Insiders show cautious optimism through measured share purchases.

Buy/Sell Ratio

1.41:1

Positive buy/sell ratio. Buying exceeds or matches selling, indicating net positive insider sentiment.

Recent Trend (3 Months)

$105K

Very strong recent buying momentum. Recent insider purchases significantly outpace sales, suggesting near-term optimism.

Insider Participation

High Buying

5 insider buyers vs. 1 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Broad-based insider buying: When multiple insiders independently decide to purchase shares, it often reflects genuine confidence rather than coordinated optics. This pattern deserves attention, especially if buying followed a price decline.

SEC Filings

ALDX - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2025

N/A

April 27, 2026
June 10, 2025
2025
DEF 14A

DEF 14A 2025

N/A

April 25, 2025
June 10, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 22, 2024
June 04, 2024
2024
DEF 14A

DEF 14A 2023

N/A

May 23, 2023
June 30, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 25, 2022
June 07, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 14, 2021
June 08, 2021
2021
DEF 14A

DEF 14A 2020

N/A

April 27, 2020
June 09, 2020
2020
DEF 14A

DEF 14A 2019

N/A

April 22, 2019
June 04, 2019
2019
DEF 14A

DEF 14A 2018

N/A

April 25, 2018
June 07, 2018
2018
DEF 14A

DEF 14A 2017

N/A

April 24, 2017
June 08, 2017
2017
Showing 1 to 10 of 12 filings