Agenus Inc.

Agenus Inc.

AGENยทNASDAQ

$3.45

+4.9%
HealthcareBiotechnology

Agenus Inc., a clinical-stage immuno-oncology company, discovers and develops immuno-oncology products in the United States and internationally. The company offers Retrocyte Display, an antibody expression platform for the identification of fully human and humanized monoclonal antibodies; and display technologies. It develops vaccine programs comprising Prophage vaccine candidate; and QS-21 Stimulon adjuvant, a saponin-based vaccine adjuvant. The company also develops Balstilimab, an anti-PD-1 antagonist that has completed Phase II clinical trial to treat second line cervical cancer; AGEN1181, an anti-CTLA-4 monospecific antibody that is in Phase 1/2 clinical trial; AGEN2373, an anti-CD137 monospecific antibody that is in Phase 1 clinical trial; AGEN1423, a tumor microenvironment conditioning anti-CD73/TGFรŸ TRAP bi-functional antibody that has completed Phase 1 clinical trial; AGEN1777, an anti-TIGIT bispecific antibodies; and AGEN1327, a human monoclonal antibody. In addition, the company develops INCAGN1876, an anti-GITR monospecific antibody; INCAGN1949, an anti-OX40 monospecific antibody; INCAGN2390, an anti-TIM-3 monospecific antibody; INCAGN2385, an anti-LAG-3 monospecific antibody; MK-4830, a monospecific antibody targeting ILT4; AGENT 797, an iNKT cells that is in Phase 1 clinical trial for solid tumors, multiple myeloma, and viral ARDS, as well as in clinical stage to treat hematological malignancies and multiple myeloma/B cells; and AGEN1884, a first-generation anti-CTLA-4 monospecific antibody. Agenus Inc. operates under ASV, Agenus, AutoSynVax, EVAMPLIX, MiNK, PSV, PhosPhoSynVax, Prophage, Retrocyte Display, and Stimulon trademarks. It has collaborations with Incyte Corporation, Merck Sharpe & Dohme, Recepta Biopharma SA, and Gilead Sciences, Inc. The company was formerly known as Antigenics Inc. and changed its name to Agenus Inc. in January 2011. Agenus Inc. was founded in 1994 and is headquartered in Lexington, Massachusetts.

At a Glance

Live Snapshot
Market Cap$143.48M
EPS-0.0034
P/E Ratio-1013.38
Earnings Date08/10/2026
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Agenus Inc. Street Expectations Map

AGEN ยท NASDAQ

Wall Street analysts project that AGEN stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 7.33, with estimates ranging from a low of 7.00 to a high of 8.00.

Lowest Target
7.00
103.16%
Consensus Target
7.33
112.74%
Highest Target
8.00
132.19%

The consensus 1-year price target stands at 7.33, with estimates ranging from a low of 7.00 to a high of 8.00.

Analyst Consensus Analysis

Upside Potential

+112.7%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

13.6% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Rare opportunity: Exceptional upside potential with strong analyst consensus creates a compelling setup. The combination of significant price target premium and tight agreement suggests high-conviction undervaluation that may attract institutional capital.

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Agenus Inc. Forward Estimates of Revenue

AGEN ยท NASDAQ
Latest Revenue
114.20M
FY 2025
Avg Estimate
136.40M
FY 2026
Estimate Range
123.64M - 149.16M
Analyst Spread

Forward Growth Analysis

Projected Growth+19.4%

Solid growth trajectory indicates healthy business performance and competitive positioning.

Analyst Coverage1 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread19%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Agenus Inc. Forward Estimates of Net Income

AGEN ยท NASDAQ
Latest Net Income
115.00K
FY 2025
Avg Estimate
23.34M
FY 2026
Estimate Range
20.50M - 26.18M
Analyst Spread

Forward Growth Analysis

Projected Growth+20196.7%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage1 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread24%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Agenus Inc. Forward Estimates of EPS

AGEN ยท NASDAQ
Latest EPS
-0.00
FY 2025
Avg Estimate
$0.79
FY 2026
Estimate Range
$0.69 - $0.88
Analyst Spread

Forward Growth Analysis

Projected Growth+23188.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage1 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread24%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Agenus Inc. Forward Estimates of EBIT

AGEN ยท NASDAQ
Latest EBIT
-20.56M
FY 2025
Avg Estimate
-65.96M
FY 2026
Estimate Range
-72.13M - -59.79M
Analyst Spread

Forward Growth Analysis

Projected Growth-220.9%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage1 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread19%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Agenus Inc. Forward Estimates of EBITDA

AGEN ยท NASDAQ
Latest EBITDA
-10.56M
FY 2025
Avg Estimate
-60.56M
FY 2026
Estimate Range
-66.23M - -54.90M
Analyst Spread

Forward Growth Analysis

Projected Growth-473.7%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage1 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread19%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Agenus Inc. Forward Estimates of SG&A Expense

AGEN ยท NASDAQ
Latest SG&A Expense
44.39M
FY 2025
Avg Estimate
75.28M
FY 2026
Estimate Range
68.23M - 82.32M
Analyst Spread

Forward Growth Analysis

Projected Growth+69.6%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage1 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread19%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Agenus Inc. Insider Positioning

AGEN ยท NASDAQ

During the last 12 months, insiders have purchased $1.01M worth of AGEN shares, with no selling activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

21.8K

94.38K

Sold

0

0.00

Net Activity

+94K

+$94K

9-12 Months

Bought

229.6K

917.36K

Sold

0

0.00

Net Activity

+917K

+$917K

Top Buyers

1
AGH

Armen Garo H

Director, Officer: See Remarks

137.7K sharesโ€ข13 transactions

$568K

2
OSJ

O'Day Steven J

Officer: Chief Medical Officer

43.5K sharesโ€ข1 transactions

$194K

3
HTL

Harrison Thomas L

Director

30.7K sharesโ€ข3 transactions

$107K

4
KCM

Klaskin Christine M

Officer: Pfo & Pao

23.0K sharesโ€ข2 transactions

$92K

5
HSB

Hirsch Susan B

Director

15.0K sharesโ€ข1 transactions

$45K

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $1.01M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

โˆž:1

Perfect buy/sell ratio. Only buying activity with zero sellingโ€”the most bullish possible insider signal.

Insider Participation

High Buying

5 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.