Adverum Biotechnologies, Inc.

Adverum Biotechnologies, Inc.

ADVMยทNASDAQ

$4.36

+0.0000%
HealthcareBiotechnology

Adverum Biotechnologies, Inc., a clinical-stage gene therapy company, develops gene therapy product candidates to treat ocular and rare diseases. Its lead product candidate is ADVM-022, a single intravitreal injection gene therapy candidate used for the treatment of patients with chronic retinal, including wet age-related macular degeneration and diabetic macular edema. Adverum Biotechnologies, Inc. has license and collaboration agreements with University of California; Cornell University; GenSight; Lexeo; and Virovek. The company was formerly known as Avalanche Biotechnologies, Inc. and changed its name to Adverum Biotechnologies, Inc. in May 2016. Adverum Biotechnologies, Inc. was incorporated in 2006 and is headquartered in Redwood City, California.

At a Glance

Live Snapshot
Market Cap$96.26M
EPS-6.6200
P/E Ratio-0.71
Earnings Date04/21/2026
advm

Adverum Biotechnologies, Inc. Street Expectations Map

ADVM ยท NASDAQ

Wall Street analysts project that ADVM stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 4.83, with estimates ranging from a low of 4.00 to a high of 5.50.

Lowest Target
4.00
-8.26%
Consensus Target
4.83
10.78%
Highest Target
5.50
26.15%

The consensus 1-year price target stands at 4.83, with estimates ranging from a low of 4.00 to a high of 5.50.

Analyst Consensus Analysis

Upside Potential

+10.8%

Moderate upside. Analysts expect positive returns but with limited margin of safety. Consider entry timing.

Analyst Agreement

31.1% spread

Good consensus alignment. Moderate target spread reflects general agreement on value drivers with some variance in assumptions.

Risk-Reward Profile

3.17x

Favorable risk-reward. Potential upside significantly exceeds downside risk, offering asymmetric return profile attractive for risk-tolerant investors.

Analyst Conviction

High

Positive outlook with reasonable agreement. Analysts generally optimistic about prospects with manageable uncertainty.

Market Sentiment Insight

Asymmetric upside: Strong return potential with favorable risk-reward profile. The limited downside relative to upside makes this an attractive risk-adjusted opportunity for growth-oriented portfolios.

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Adverum Biotechnologies, Inc. Forward Estimates of Revenue

ADVM ยท NASDAQ
Latest Revenue
1.00M
FY 2024
Avg Estimate
200.00K
FY 2025
Estimate Range
200.00K - 200.00K
Analyst Spread

Forward Growth Analysis

Projected Growth-80.0%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Adverum Biotechnologies, Inc. Forward Estimates of Net Income

ADVM ยท NASDAQ
Latest Net Income
-130.93M
FY 2024
Avg Estimate
-194.99M
FY 2025
Estimate Range
-223.60M - -94.25M
Analyst Spread

Forward Growth Analysis

Projected Growth-48.9%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread66%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Adverum Biotechnologies, Inc. Forward Estimates of EPS

ADVM ยท NASDAQ
Latest EPS
-6.62
FY 2024
Avg Estimate
$-8.04
FY 2025
Estimate Range
$-11.30 - $-4.76
Analyst Spread

Forward Growth Analysis

Projected Growth-21.5%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread81%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Adverum Biotechnologies, Inc. Forward Estimates of EBIT

ADVM ยท NASDAQ
Latest EBIT
-139.16M
FY 2024
Avg Estimate
-40.00K
FY 2025
Estimate Range
-40.00K - -40.00K
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

advm

Adverum Biotechnologies, Inc. Forward Estimates of EBITDA

ADVM ยท NASDAQ
Latest EBITDA
-135.51M
FY 2024
Avg Estimate
-40.00K
FY 2025
Estimate Range
-40.00K - -40.00K
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Adverum Biotechnologies, Inc. Forward Estimates of SG&A Expense

ADVM ยท NASDAQ
Latest SG&A Expense
63.12M
FY 2024
Avg Estimate
3.56M
FY 2025
Estimate Range
3.56M - 3.56M
Analyst Spread

Forward Growth Analysis

Projected Growth-94.4%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Adverum Biotechnologies, Inc. Insider Positioning

ADVM ยท NASDAQ

During the last 12 months, insiders have purchased $966K and sold $18.21M worth of ADVM shares, resulting in $17.24M of net selling activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

117.6K

506.92K

Sold

0

0.00

Net Activity

+507K

+$507K

6-9 Months

Bought

61.1K

258.00K

Sold

1.1M

4.61M

Net Activity

-4.4M

-$4.35M

9-12 Months

Bought

86.7K

201.24K

Sold

199.5K

13.60M

Net Activity

-13.4M

-$13.40M

Top Buyers

1
FL

Fischer Laurent

Director, Officer: Ceo, President And Director

128.7K sharesโ€ข2 transactions

$554K

2
SP

Soparkar Peter

Officer: Chief Operating Officer

50.0K sharesโ€ข1 transactions

$211K

3
HS

Hong Soo

Director

10.4K sharesโ€ข1 transactions

$24K

4
NCD

Nicholson, C. David

Director

10.4K sharesโ€ข1 transactions

$24K

5
WSM

Whitcup Scott M

Director

10.4K sharesโ€ข1 transactions

$24K

Top Sellers

1
FL

Fischer Laurent

Director, Officer: Ceo, President And Director

68.0K sharesโ€ข1 transactions

$9.14M

2
LBM

Leonard Braden Michael

10 Percent Owner

1.1M sharesโ€ข4 transactions

$4.61M

3
SP

Soparkar Peter

Officer: Chief Operating Officer

40.0K sharesโ€ข1 transactions

$2.75M

4
SS

Seyedkazemi Setareh

Officer: Chief Development Officer

48.5K sharesโ€ข2 transactions

$906K

5
RLM

Rubinstein Linda M

Officer: Chief Financial Officer

35.0K sharesโ€ข1 transactions

$697K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $17.24M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.05:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Insider Participation

Balanced

5 insider buyers and 5 sellers. Equal participation suggests mixed or neutral insider views.