Thank you, Ken. Good morning, and thanks for joining us today. I'm pleased to report on strong financial results for the first quarter 2022 at Cboe Global Markets, reflecting the continued strength of our business. During the quarter, year-over-year, we grew net revenue 14% to a record $418 million, and adjusted diluted earnings per share grew by 13% to a record $1.73. Our solid first quarter results were driven by the ongoing expansion and diversification of our business, with strong trading activity in our cash equity businesses, higher volumes in our proprietary index products, and increased demand for our suite of data and access solutions. Our Options business had an outstanding quarter with a strong contribution from our proprietary index products and solid results from our multi-listed options business. Our proprietary index products resonated well with our customers as volatility continued to remain steadily elevated around the world and market participants engaged with our product suite to manage risk. Average daily volume increased 42% in SPX options year-over-year, with VIX options increasing slightly year-over-year and up 18% over the fourth quarter 2021. Multi-listed options trading ADV increased 2% year-over-year to a new record of 11 million contracts per day. Additionally, our European Equities segment had a very strong quarter. Net revenue increased 37% as industry average daily notional value traded increased 31%, and market share rose 5 percentage points year-over-year to 21.8%, the highest since the first quarter of 2019. These results were driven by, not just favorable market backdrop, but by the expansion of our data and analytics services to help clients improve the quality of their executions and enhance their overall trading experience across our lit and dark order books, periodic auctions, and Cboe BIDS Europe. On the U.S. equities side, we were pleased to launch periodic auctions on our BYX exchange earlier this month and hope to replicate the success we've had with our European periodic auctions offering. Turning to Asia Pacific. Cboe Japan market share increased considerably during the first quarter to 3.8%, up from 2.9% in the fourth quarter 2021, as a result of a new liquidity provider program designed to attract new volume to the market. We are excited to have a growing footprint in Japan, which is the fourth largest equities market in the world by volume traded. In Australia, volumes remained strong across our equities business, and we are also preparing to list Asia Pacific's first crypto ETFs on Cboe Australia in the coming weeks. We’re excited to be helping to bring these innovative products to market. Importantly, while achieving strong results, we continued to successfully execute on key initiatives to advance our corporate strategy to innovate, integrate and grow our business globally. In February, we completed the migration of MATCHNow, the largest equities alternative trading system in Canada, to Cboe technology creating a unified trading experience for all of our North American customers. Along with this technology migration, we launched Cboe BIDS Canada, bringing a new and enhanced blocktrading offering to the Canadian equities market. It's important to note that these enhancements are already benefiting from our platform with the migration of MATCHNow improving latency and institutional activity increasing with over 10 sponsoring brokers signed on as Cboe BIDS Canada sponsors. We look forward to further expanding our footprint in the Canadian equities market with the expected close of our acquisition of NEO later this quarter, subject to regulatory approvals and customary closing conditions. We also announced plans to migrate Cboe Australia to our world-class technology platform in February 2023, pending regulatory review and approval, and released technical specifications for this migration a month ahead of schedule. We appreciate the early engagement with customers in Australia on this important initiative and we will be working closely with them throughout the year as they make their preparations for the migration. As we continue to broaden and evolve Cboe, our global network gives us the unmatched ability to efficiently scale and expand our business in new ways, both organically and inorganically. As we architect the business for future growth, I was incredibly excited to announce several leadership changes last month, including the appointment of David Howson to President of Cboe on May 12. Many of you know Dave well as he currently serves as President of our European and Asia Pacific segments and has done a remarkable job working with the team and our customers to successfully grow these businesses. His track record speaks volumes, and he has spearheaded the development and execution of some of Cboe's most innovative products and services. Dave is planning to relocate from London to Chicago and will oversee Cboe's business lines globally. Please welcome Dave as he joins us on the call today. I believe the enhancements to our management team showcase our deep bench of talent and position Cboe well to advance our global expansion strategy. As mentioned last quarter, we are focused on executing on the transformational opportunities we see in three core areas of our business; Data and Access Solutions, Derivatives and Cboe Digital. We continue to fuel these opportunities by executing against our ongoing strategy which remains consistent; leverage our superior technology, further strengthen our core proprietary products, increase recurring revenue, and expand our product line by geography and asset class. During the first quarter, we made solid progress advancing each of these core areas of our business. Let me begin with Data and Access Solutions, which delivered record results during the quarter with revenues increasing 18%. This growth was driven by continued demand for access to our exchanges, proprietary market data and new subscribers to Cboe's frontend platforms. Cboe Global Cloud, a cloud-based market data streaming service we launched during the fourth quarter, continues to gain traction with customers. This new service aims to increase access to our unique data set to customers globally. We plan to further expand the data set offered via Cboe Global Cloud this summer with the addition of European equities data, which we believe will further expand the customer base accessing our data via the cloud. We continue to believe this business is positioned incredibly well moving forward. Given our confidence, we are increasing our 2022 targeted organic growth rate for Data and Access Solutions to 8% to 11% from 7% to 10%. Our unique product set, coupled with our geographic and asset class diversification, enables us to meet the needs of customers from London to Tokyo, Chicago to Singapore and everywhere in between. As the world continues to grapple with uncertainty caused by the war in Ukraine, rising inflation and interest rates, and the ongoing challenges with the pandemic, market participants have increasingly turned to derivatives and volatility vehicles to help mitigate risk. We continue to innovate and expand our derivatives business globally to meet this ongoing customer need by growing 24x5 trading in SPX and VIX options; expanding our popular SPX Weeklys options offering to provide expirations every trading day of the week starting in May; and launching Nanos, a new smaller-sized product designed for the retail trader. Earlier, I noted our overall strong volumes across our proprietary products franchise as we continue to see solid momentum trading in SPX and VIX Options since launching 24x5 trading in November 2021. During the first quarter, average daily volume in SPX options during Global Trading Hours increased 164% year-over-year, more than double the volume prior to the launch of 24x5. Additionally, average daily volume in VIX Options during Global Trading Hours increased 14% year-over-year while VIX Futures volumes increased 19%. Although still in its early days, the incremental volume we are seeing as a result of 24x5 enhancements has already generated an attractive return on our 2021 investment. Last week, we added Tuesday expirations to our SPX Weeklys complex and plan to add Thursday expirations beginning May 11. These new listings build on the success of our SPX Weeklys, which currently include Monday, Wednesday, and Friday expiries. Since we launched SPX Weeklys in 2005, they have become one of the most actively traded products, accounting for 70% of total SPX options volume, as they allow investors to manage their short-term U.S. equity market exposure and execute trading strategies with even greater frequency, precision and flexibility. We have received very positive feedback from a broad range of market participants, and we are off to a strong start. On Tuesday, we saw over 600,000 Tuesday expiry contracts traded. Last month, we were excited to launch Nanos, a first of its kind options contract designed to make trading more accessible for the retail trader. We have been pleased with initial volumes, which have topped 3,500 contracts on several days, and we plan to continue to expand the network of retail brokers offering this product. We expect this market to continue to flourish over time and we look forward to engaging with this growing retail segment. Turning now to Europe. Our European Derivatives business continues to gain momentum and we are pleased with the progress made since launch last September. Volumes continue to grow and we reported over 6,000 contracts traded in the first quarter, an almost four-fold increase on last quarter's volumes. Earlier this week, we launched futures and options on four additional country indices; Italy, Spain, Sweden and Norway. This second phase of products broadens our equity index product suite to cover additional key European markets, providing customers with the tools to efficiently manage their European index exposures via a single marketplace. The expansion of our global derivatives franchise is laying a strong foundation to build upon throughout the rest of the year as we help clients around the world navigate risk. Turning now to Cboe Digital and our planned acquisition of ErisX, which remains on track to close very soon, subject to customary closing conditions. ErisX will provide Cboe with spot trading, data, and clearing capabilities for digital assets and derivatives trading, clearing and data through its regulated futures exchange and clearing house. This is a pivotal moment for Cboe as we reenter the digital asset market and we couldn't be more excited to apply our blueprint of success; operating trusted, transparent, regulated markets to digital assets. As we've said before, we believe Cboe can play a guiding role in shaping the trajectory of this revolutionary market. We have been actively engaged with regulators as they shape policy for this emerging asset class. Additionally, the ErisX application for margin futures is currently in review at the CFTC. We look forward to welcoming the ErisX team to Cboe and accomplishing great things together as Cboe Digital. We are focused on driving durable growth here at Cboe, and I believe the targeted investments we are making across the ecosystem today not only help us diversify our product set and strengthen our flywheel, but also allow us to enhance the robustness of our revenue growth. The ability to harvest investments over various periods of time, from near-term contributors like Tuesday/Thursday expiries and 24x5 to longer term investments in products like Nanos, position Cboe well to grow for years to come. And now, I will turn over to Brian.