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Healthcare - Biotechnology - NASDAQ - CA
$ 0.2139
3.33 %
$ 12.9 M
Market Cap
-0.07
P/E
1. INTRINSIC VALUE

This DCF valuation model was last updated on Jan, 18, 2025.

The intrinsic value of one APTO stock under the worst case scenario is HIDDEN Compared to the current market price of 0.214 USD, Aptose Biosciences Inc. is HIDDEN

This DCF valuation model was last updated on Jan, 18, 2025.

The intrinsic value of one APTO stock under the base case scenario is HIDDEN Compared to the current market price of 0.214 USD, Aptose Biosciences Inc. is HIDDEN

This DCF valuation model was last updated on Jan, 18, 2025.

The intrinsic value of one APTO stock under the best case scenario is HIDDEN Compared to the current market price of 0.214 USD, Aptose Biosciences Inc. is HIDDEN

2. FUNDAMENTAL ANALYSIS
FINANCIALS
0 REVENUE
0.00%
-52.4 M OPERATING INCOME
-22.92%
-51.2 M NET INCOME
-22.44%
-44.6 M OPERATING CASH FLOW
-37.96%
9.96 M INVESTING CASH FLOW
-66.87%
6.91 M FINANCING CASH FLOW
5856.90%
0 REVENUE
0.00%
-6.96 M OPERATING INCOME
5.17%
-6.95 M NET INCOME
4.12%
-10.4 M OPERATING CASH FLOW
-79.58%
0 INVESTING CASH FLOW
0.00%
10 M FINANCING CASH FLOW
110.52%
Balance Sheet Aptose Biosciences Inc.
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Current Assets 11.9 M
Cash & Short-Term Investments 9.25 M
Receivables 0
Other Current Assets 2.64 M
Non-Current Assets 1.1 M
Long-Term Investments 0
PP&E 1.1 M
Other Non-Current Assets 0
Current Liabilities 15.3 M
Accounts Payable 6.05 M
Short-Term Debt 394 K
Other Current Liabilities 8.83 M
Non-Current Liabilities 621 K
Long-Term Debt 621 K
Other Non-Current Liabilities 0
EFFICIENCY
Earnings Waterfall Aptose Biosciences Inc.
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Revenue 0
Cost Of Revenue 475 K
Gross Profit -475 K
Operating Expenses 52.4 M
Operating Income -52.4 M
Other Expenses -1.15 M
Net Income -51.2 M
RATIOS
0.00% GROSS MARGIN
0.00%
0.00% OPERATING MARGIN
0.00%
0.00% NET MARGIN
0.00%
1765.15% ROE
1765.15%
-394.23% ROA
-394.23%
1804.76% ROIC
1804.76%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis Aptose Biosciences Inc.
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Net Income -51.2 M
Depreciation & Amortization 466 K
Capital Expenditures -29 K
Stock-Based Compensation 3.65 M
Change in Working Capital 2.45 M
Others 2.5 M
Free Cash Flow -44.6 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets Aptose Biosciences Inc.
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APTO has no price targets from Wall Street.
4. DIVIDEND ANALYSIS
5. COMPETITION
6. Ownership
Insider Ownership Aptose Biosciences Inc.
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Sold
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
0 USD 0
Bought
32.5 K USD 1
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
Date Value Insider Amount Avg Price
1 month ago
Nov 25, 2024
Bought 20 K USD
Rice William G.
Chair, President & CEO
+ 100000
0.2 USD
1 month ago
Nov 25, 2024
Bought 12.5 K USD
Rice William G.
Chair, President & CEO
+ 50000
0.25 USD
1 year ago
Sep 22, 2023
Bought 53.4 K USD
Seizinger Bernd R.
Director
+ 17000
3.14 USD
2 years ago
Sep 19, 2022
Bought 6.83 K USD
Rice William G.
Chair, President & CEO
+ 10000
0.6834 USD
2 years ago
Jun 06, 2022
Bought 9.68 K USD
Rice William G.
Chair, President & CEO
+ 10000
0.9681 USD
3 years ago
Dec 20, 2021
Bought 14.5 K USD
BURGER DENIS R
Director
+ 10000
1.449 USD
3 years ago
Dec 16, 2021
Bought 28 K USD
PLATZER ERICH
Director
+ 20000
1.4 USD
3 years ago
Dec 16, 2021
Bought 41.4 K USD
PLATZER ERICH
Director
+ 30000
1.38 USD
3 years ago
Dec 16, 2021
Bought 68.5 K USD
PLATZER ERICH
Director
+ 50000
1.37 USD
3 years ago
Dec 15, 2021
Bought 118 K USD
PLATZER ERICH
Director
+ 100000
1.176 USD
3 years ago
Dec 15, 2021
Bought 35.7 K USD
PLATZER ERICH
Director
+ 30000
1.19 USD
3 years ago
Dec 15, 2021
Bought 24 K USD
PLATZER ERICH
Director
+ 20000
1.198 USD
3 years ago
Dec 15, 2021
Bought 139 K USD
PLATZER ERICH
Director
+ 120000
1.159 USD
3 years ago
Dec 16, 2021
Bought 20 K USD
Rice William G.
Chair, President & CEO
+ 13183
1.52 USD
3 years ago
Dec 15, 2021
Bought 20 K USD
Rice William G.
Chair, President & CEO
+ 17822
1.12 USD
3 years ago
Nov 26, 2021
Bought 20 K USD
Rice William G.
Chair, President & CEO
+ 8643
2.31 USD
3 years ago
Nov 19, 2021
Bought 25.6 K USD
Bejar Rafael
Sr. VP, Chief Medical Officer
+ 10000
2.56 USD
3 years ago
Aug 03, 2021
Bought 151 K USD
Wilson Donald R. Jr.
10 percent owner
+ 57199
2.647 USD
3 years ago
Aug 05, 2021
Sell 157 K USD
Wilson Donald R. Jr.
10 percent owner
- 60000
2.62 USD
3 years ago
Jul 02, 2021
Bought 20 K USD
Rice William G.
Chair, President & CEO
+ 6081
3.2886 USD
3 years ago
Jun 21, 2021
Sell 51.6 K USD
Whitehead Warren
Director
- 15400
3.35 USD
3 years ago
Jun 22, 2021
Sell 31.1 K USD
Whitehead Warren
Director
- 9600
3.24 USD
4 years ago
Dec 22, 2020
Sell 40.1 K USD
Whitehead Warren
Director
- 10000
4.01 USD
4 years ago
Dec 22, 2020
Sell 41.1 K USD
Whitehead Warren
Director
- 10000
4.11 USD
4 years ago
Jul 10, 2020
Sell 766 K USD
Chow Gregory K.
Executive VP & CFO
- 126668
6.05 USD
4 years ago
Jul 10, 2020
Sell 1.02 M USD
Rice William G.
Chair, President & CEO
- 168891
6.05 USD
4 years ago
Jul 10, 2020
Sell 380 K USD
Marango Jotin
Senior VP, Chief Bus. Officer
- 62835
6.05 USD
4 years ago
Jul 02, 2020
Sell 133 K USD
Marango Jotin
Senior VP, Chief Bus. Officer
- 20946
6.3398 USD
4 years ago
Jun 23, 2020
Sell 92 K USD
Whitehead Warren
Director
- 13000
7.08 USD
4 years ago
Jun 23, 2020
Sell 35.8 K USD
Whitehead Warren
Director
- 5000
7.17 USD
4 years ago
Jun 24, 2020
Sell 80.8 K USD
Whitehead Warren
Director
- 12000
6.73 USD
4 years ago
Jun 24, 2020
Sell 33.9 K USD
Whitehead Warren
Director
- 5000
6.78 USD
4 years ago
Mar 25, 2020
Bought 19.8 K USD
Rice William G.
Chair, President & CEO
+ 3400
5.8244 USD
5 years ago
Oct 24, 2019
Bought 19.2 K USD
Rice William G.
Chairman, President & CEO
+ 10000
1.92 USD
5 years ago
Jun 05, 2019
Bought 13.8 K USD
Chow Gregory K.
Senior VP & CFO
+ 7500
1.842 USD
5 years ago
Apr 18, 2019
Bought 18.5 K USD
Rice William G.
Chair, President & CEO
+ 10000
1.8507 USD
5 years ago
Mar 19, 2019
Bought 11 K USD
PLATZER ERICH
Director
+ 5000
2.194 USD
5 years ago
Mar 19, 2019
Bought 32.8 K USD
PLATZER ERICH
Director
+ 15000
2.189 USD
5 years ago
Mar 19, 2019
Sell 11 K USD
PLATZER ERICH
Director
- 5000
2.194 USD
5 years ago
Mar 19, 2019
Sell 32.8 K USD
PLATZER ERICH
Director
- 15000
2.189 USD
5 years ago
Mar 14, 2019
Bought 19 K USD
Rice William G.
Chair, President & CEO
+ 10000
1.8993 USD
5 years ago
Mar 13, 2019
Bought 8.93 K USD
Chow Gregory K.
Senior VP & CFO
+ 5000
1.7856 USD
5 years ago
Mar 13, 2019
Bought 17.4 K USD
Chow Gregory K.
Senior VP & CFO
+ 10000
1.7394 USD
7. News
Aptose Announces Positive Decision by Nasdaq Hearings Panel SAN DIEGO and TORONTO, Dec. 19, 2024 (GLOBE NEWSWIRE) -- Aptose Biosciences Inc. (“Aptose” or the “Company”) (NASDAQ: APTO, TSX: APS), a clinical-stage precision oncology company developing highly differentiated targeted agents to treat hematologic malignancies, today announced that the Nasdaq Hearings Panel (“Panel”) has granted the Company's request for an extension to evidence compliance with all applicable criteria for continued listing on The Nasdaq Stock Market. On or before March 31, 2025, the Company will be required to demonstrate compliance with NASDAQ Listing Rule 5550(b)(1) requiring the Company to have a minimum of $2.5 million in shareholders' equity (the “Equity Rule”) and NASDAQ Listing Rule 5550(a)(2) requiring the Company to have a minimum bid price of $1.00 (the “Minimum Bid Price Rule”). globenewswire.com - 1 month ago
Aptose Announces Publication of Preclinical Data in AACR Journal Demonstrating Tuspetinib's Unique Mechanism of Action and Synthetic Lethality on AML Cells When Combined with Venetoclax Aptose Announces Publication of Preclinical Data in AACR Journal Demonstrating Tuspetinib's Unique Mechanism of Action and Synthetic Lethality on AML Cells globenewswire.com - 1 month ago
Aptose Clinical Data Featured in Poster Presentation at the 2024 ASH Annual Meeting Support Tuspetinib Triple Drug Therapy for Newly Diagnosed AML TUS+VEN+AZA Triplet Frontline Therapy in Newly Diagnosed AML Patients Now Enrolling at U.S. Sites TUS and TUS+VEN Broadly Active Across AML Populations, with Favorable Safety TUS-based therapies are active in FLT3 wildtype, representing ~70% of AML patients TUS Targets VEN Resistance Mechanisms, Enabling TUS+VEN to Achieve Responses in Difficult-to-treat Prior-VEN Failure AML SAN DIEGO and TORONTO, Dec. 09, 2024 (GLOBE NEWSWIRE) -- Aptose Biosciences Inc. (“Aptose” or the “Company”) (NASDAQ: APTO, TSX: APS), a clinical-stage precision oncology company developing highly differentiated targeted agents to treat hematologic malignancies, today featured a wealth of clinical data for Aptose's lead compound tuspetinib (TUS) in a poster presentation at the 66th American Society of Hematology (ASH) Annual Meeting in San Diego. Poster title: “Phase 1 Safety and Efficacy of Tuspetinib Plus Venetoclax Combination Therapy in Study Participants with Relapsed or Refractory Acute Myeloid Leukemia (AML) Support Exploration of Triplet Combination Therapy of Tuspetinib Plus Venetoclax and Azacitidine for Newly Diagnosed AML” Key Findings and Messages: TUS+VEN+AZA triplet trial is proceeding in newly diagnosed AML patients TUS+VEN retains activity in the difficult-to-treat prior-VEN AML population TUS+VEN is active in FLT3 wildtype, representing ~70% of AML patients TUS+VEN is well tolerated and can be safely co-administered TUS+VEN is active across broad populations of R/R AML Combination of TUS with VEN may avoid VEN resistance TUS+VEN+AZA triplet may establish a more effective, mutation agnostic standard of care for chemotherapy ineligible AML patients Tuspetinib (TUS), being developed by Aptose and originally created by Hanmi Pharmaceutical Co., is being advanced as the TUS+VEN+AZA triplet (tuspetinib+venetoclax+azacitidine) for frontline therapy of newly diagnosed AML patients ineligible for intensive chemotherapy. globenewswire.com - 1 month ago
Aptose Signs CRADA with NCI to Develop Tuspetinib for AML and MDS in Newly Launched MyeloMATCH Precision Medicine Trials Aptose's AML drug tuspetinib selected for NCI's prestigious clinical research program for ability to target broad spectrum of AML and MDS populations globenewswire.com - 1 month ago
Aptose Biosciences Inc. Announces Closing of $8 Million Public Offering SAN DIEGO and TORONTO, Nov. 25, 2024 (GLOBE NEWSWIRE) -- Aptose Biosciences Inc. (“Aptose” or the “Company”) (NASDAQ: APTO, TSX: APS), a clinical-stage precision oncology company developing highly differentiated oral targeted agents to treat hematologic malignancies, today announced the closing of its previously announced "reasonable best efforts" public offering with participation from the CEO and existing and new healthcare focused investors for the purchase and sale of 40,000,000 common shares at a price of $0.20 per share and warrants to purchase up to 20,000,000 common shares (the “Offering”). The warrants have an exercise price of $0.25 per share, are exercisable immediately and will expire five years from the issuance date. globenewswire.com - 1 month ago
Aptose Biosciences Inc. Announces Pricing of $8 Million Public Offering SAN DIEGO and TORONTO, Nov. 22, 2024 (GLOBE NEWSWIRE) -- Aptose Biosciences Inc. (“Aptose” or the “Company”) (NASDAQ: APTO, TSX: APS), a clinical-stage precision oncology company developing highly differentiated oral targeted agents to treat hematologic malignancies, today announced the pricing of its "reasonable best efforts" public offering with participation from the CEO and existing and new healthcare focused investors for the purchase and sale of up to 40,000,000 shares of common stock and warrants to purchase up to 20,000,000 shares of common stock at a combined offering price of $0.20 per share and accompanying warrant (the “Offering”). The Company expects to receive aggregate gross proceeds of approximately $8 million, before deducting placement agent fees and other offering expenses, and assuming no exercise of the warrants. globenewswire.com - 1 month ago
Aptose Initiates TUSCANY Phase 1/2 Study for Newly Diagnosed AML Patients to Receive Tuspetinib-based Triplet Therapy TUSCANY study is open to enroll patients to receive TUS+VEN+AZA triplet at select US sites Favorable safety and broad clinical activity make tuspetinib an ideal agent to combine with venetoclax and azacitidine to potentially address larger AML populations Study execution update is expected during ASH 2024 SAN DIEGO and TORONTO, Nov. 20, 2024 (GLOBE NEWSWIRE) -- Aptose Biosciences Inc. (“Aptose” or the “Company”) (NASDAQ: APTO, TSX: APS), a clinical-stage precision oncology company developing highly differentiated oral targeted agents to treat hematologic malignancies, today announced initiation of the TUSCANY study, tuspetinib (TUS) in combination therapy with azacitidine (AZA) and venetoclax (VEN) as a frontline triplet combination therapy for patients newly diagnosed with acute myeloid leukemia, or AML. The trial is being conducted at multiple U.S. clinical sites. globenewswire.com - 1 month ago
Aptose Reports Results for the Third Quarter 2024 Aptose and Hanmi Pharmaceutical Co-developing Triplet Therapy of Tuspetinib with Azacitidine and Venetoclax for Newly Diagnosed AML Aptose and Hanmi Pharmaceutical Co-developing Triplet Therapy of Tuspetinib with Azacitidine and Venetoclax for Newly Diagnosed AML globenewswire.com - 2 months ago
Aptose Announces Results from Special Meeting of Shareholders SAN DIEGO and TORONTO, Sept. 05, 2024 (GLOBE NEWSWIRE) -- Aptose Biosciences Inc. (“Aptose” or the “Company”) (NASDAQ: APTO, TSX: APS), a clinical-stage precision oncology company developing tuspetinib, a highly differentiated oral kinase inhibitor for the treatment of patients with acute myeloid leukemia (AML), announced the voting results from its special meeting of shareholders held today, September 5, 2024 (the “Meeting”). globenewswire.com - 4 months ago
Aptose Receives $10 Million Through a Facility Agreement with Hanmi; Negotiating Future Collaboration Agreement with Hanmi to Jointly Develop Tuspetinib Aptose Receives $10 Million Through a Facility Agreement with Hanmi; Negotiating Future Collaboration Agreement with Hanmi to Jointly Develop Tuspetinib globenewswire.com - 4 months ago
Aptose Announces Adjournment of its Special Meeting of Shareholders SAN DIEGO and TORONTO, Aug. 15, 2024 (GLOBE NEWSWIRE) -- Aptose Biosciences Inc. (“Aptose” or the “Company”) (NASDAQ: APTO, TSX: APS), a clinical-stage precision oncology company developing highly differentiated oral targeted agents to treat hematologic malignancies, today announced that its special meeting of shareholders (the "Meeting") convened on August 15, 2024, at 1:00 p.m. (ET) has been adjourned to September 5, 2024 at 1 p.m. globenewswire.com - 5 months ago
Aptose Reports Results for the Second Quarter 2024 TUS+VEN+HMA Triplet Protocol in Frontline Therapy for Newly Diagnosed AML was Reviewed by the FDA and Allowed to Proceed Abstract Supporting Exploration of the TUS+VEN+AZA Triplet in Frontline Therapy for Newly Diagnosed AML has been Submitted to the 2025 Annual Meeting of the American Society of Hematology (ASH) SAN DIEGO and TORONTO, Aug. 08, 2024 (GLOBE NEWSWIRE) -- Aptose Biosciences Inc. (“Aptose” or the “Company”) (NASDAQ: APTO, TSX: APS), a clinical-stage precision oncology company developing highly differentiated oral targeted agents to treat hematologic malignancies, today announced financial results for the three months ended June 30, 2024, and provided a corporate update. “We are pleased that our triplet protocol of tuspetinib with venetoclax and azacitidine (TUS+VEN+AZA) has been allowed to proceed at the 40 mg dose of tuspetinib, a dose that as a single agent and in doublet therapy has been shown to be safe and active,” said William G. globenewswire.com - 5 months ago
8. Profile Summary

Aptose Biosciences Inc. APTO

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COUNTRY CA
INDUSTRY Biotechnology
MARKET CAP $ 12.9 M
Dividend Yield 0.00%
Description Aptose Biosciences Inc., a clinical-stage biotechnology company, discovers and develops personalized therapies addressing unmet medical needs in oncology primarily in the United States. Its clinical programs include APTO-253, which is in Phase 1a/b clinical trial for the treatment of patients with relapsed or refractory blood cancers, including acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (HR MDS); and HM43239 that is in Phase 1/2 clinical trial to treat patients with relapsed or refractory AML. The company also develops luxeptinib, which is in Phase 1a/b clinical trial for treating patients with relapsed or refractory B-cell malignancies, including chronic lymphocytic leukemia, small lymphocytic lymphoma, and various non-Hodgkin's lymphomas, as well as AML and HR MDS; and APL-581, a dual bromodomain and extra-terminal domain motif protein and kinase inhibitor program. It has agreements with CrystalGenomics, Inc. and OHM Oncology. The company was formerly known as Lorus Therapeutics Inc. and changed its name to Aptose Biosciences Inc. in August 2014. Aptose Biosciences Inc. was incorporated in 1986 and is headquartered in Toronto, Canada.
Contact 251 Consumers Road, Toronto, ON, M2J 4R3 https://www.aptose.com
IPO Date March 16, 1992
Employees 35
Officers Dr. William G. Rice Ph.D. Chairman, President & Chief Executive Officer Mr. Fletcher Payne Senior Vice President, Chief Financial Officer, Chief Business Officer & Secretary Dr. Rafael Bejar M.D., Ph.D. Senior Vice President & Chief Medical Officer Dr. Marc Wiles Ph.D. Senior Vice President of Regulatory Affairs