image
Healthcare - Biotechnology - NASDAQ - US
$ 2.87
-13.3 %
$ 62.2 M
Market Cap
-0.93
P/E
1. INTRINSIC VALUE

Aileron Therapeutics, Inc. operates as a clinical stage chemoprotection oncology company in the United States. The company is developing ALRN-6924, which is in Phase 1 trial for solid tumor and lymphoma; Phase 2a clinical trial to treat peripheral T-cell lymphoma; Phase I clinical trial for the treatment of acute myeloid leukemia (AML) and advanced myelodysplastic syndrome (MDS); Phase 1b trial to test the combination of ALRN-6924 and cytarabine, or Ara-C, in patients with MDS; and a Phase 2a combination trial of ALRN-6924 and palbociclib in patients with tumors harboring MDM2 amplifications co-amplifications, as well as for patients with p53-mutated small cell lung cancer that has completed Phase 1b clinical trial.[ Read More ]

The intrinsic value of one ALRN stock under the base case scenario is HIDDEN Compared to the current market price of 2.87 USD, Aileron Therapeutics, Inc. is HIDDEN

2. FUNDAMENTAL ANALYSIS

Price Chart ALRN

image
FINANCIALS
0 REVENUE
0.00%
-16.3 M OPERATING INCOME
41.13%
-15.7 M NET INCOME
42.43%
-19.8 M OPERATING CASH FLOW
20.34%
16.2 M INVESTING CASH FLOW
-38.79%
15.8 M FINANCING CASH FLOW
0.00%
0 REVENUE
0.00%
-6.07 M OPERATING INCOME
32.84%
-5.85 M NET INCOME
34.61%
-3.82 M OPERATING CASH FLOW
54.48%
0 INVESTING CASH FLOW
0.00%
-446 K FINANCING CASH FLOW
-2.44%
Balance Sheet Decomposition Aileron Therapeutics, Inc.
image
Current Assets 18.3 M
Cash & Short-Term Investments 17.3 M
Receivables 0
Other Current Assets 953 K
Non-Current Assets 87.7 M
Long-Term Investments 0
PP&E 19 K
Other Non-Current Assets 87.7 M
Current Liabilities 4.38 M
Accounts Payable 1.19 M
Short-Term Debt 96 K
Other Current Liabilities 3.1 M
Non-Current Liabilities 3.33 M
Long-Term Debt 0
Other Non-Current Liabilities 3.33 M
EFFICIENCY
Earnings Waterfall Aileron Therapeutics, Inc.
image
Revenue 0
Cost Of Revenue 119 K
Gross Profit -119 K
Operating Expenses 16.3 M
Operating Income -16.3 M
Other Expenses -544 K
Net Income -15.7 M
RATIOS
0.00% GROSS MARGIN
0.00%
0.00% OPERATING MARGIN
0.00%
0.00% NET MARGIN
0.00%
-228.43% ROE
-228.43%
-14.84% ROA
-14.84%
-234.69% ROIC
-234.69%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis Aileron Therapeutics, Inc.
image
Net Income -15.7 M
Depreciation & Amortization 119 K
Capital Expenditures 0
Stock-Based Compensation 1.19 M
Change in Working Capital -5.38 M
Others -403 K
Free Cash Flow -19.8 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets Aileron Therapeutics, Inc.
image
ALRN has no price targets from Wall Street.
4. DIVIDEND ANALYSIS
0.00% DIVIDEND YIELD
0 USD DIVIDEND PER SHARE
5. COMPETITION
6. Ownership
Insider Ownership Aileron Therapeutics, Inc.
image
Sold
0-3 MONTHS
0 USD 0
3-6 MONTHS
143 K USD 1
6-9 MONTHS
225 K USD 1
9-12 MONTHS
0 USD 0
Bought
0 USD 0
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
10.7 K USD 1
9-12 MONTHS
Date Value Insider Amount Avg Price
5 months ago
Jun 14, 2024
Sell 6.27 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 1900
3.3 USD
5 months ago
Jun 17, 2024
Sell 15.3 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 4707
3.25 USD
5 months ago
Jun 10, 2024
Sell 31.6 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 9577
3.3 USD
5 months ago
Jun 11, 2024
Sell 17.1 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 5250
3.25 USD
5 months ago
Jun 11, 2024
Sell 1.68 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 502
3.35 USD
5 months ago
Jun 12, 2024
Sell 30.4 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 9341
3.25 USD
5 months ago
Jun 12, 2024
Sell 3.27 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 1
3.275 USD
5 months ago
Jun 05, 2024
Sell 20.8 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 6291
3.3 USD
5 months ago
Jun 06, 2024
Sell 3.6 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 1100
3.27 USD
5 months ago
Jun 06, 2024
Sell 10.5 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 3184
3.3 USD
5 months ago
Jun 07, 2024
Sell 5.08 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 1564
3.25 USD
5 months ago
Jun 07, 2024
Sell 581 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 176
3.3 USD
6 months ago
May 01, 2024
Sell 12.7 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 3100
4.1 USD
6 months ago
May 01, 2024
Sell 411 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 100
4.11 USD
6 months ago
May 01, 2024
Sell 7.21 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 1750
4.12 USD
6 months ago
May 01, 2024
Sell 1.57 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 380
4.13 USD
6 months ago
May 01, 2024
Sell 6.63 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 1600
4.145 USD
6 months ago
May 01, 2024
Sell 2.78 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 670
4.15 USD
6 months ago
May 01, 2024
Sell 1.67 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 400
4.18 USD
6 months ago
May 01, 2024
Sell 33.7 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 7923
4.25 USD
6 months ago
May 01, 2024
Sell 1.32 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 310
4.26 USD
6 months ago
May 01, 2024
Sell 1.35 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 317
4.265 USD
6 months ago
May 01, 2024
Sell 427 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 100
4.27 USD
6 months ago
May 01, 2024
Sell 855 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 200
4.275 USD
6 months ago
May 01, 2024
Sell 1.44 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 337
4.28 USD
6 months ago
May 01, 2024
Sell 857 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 200
4.285 USD
6 months ago
May 01, 2024
Sell 12.5 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 2903
4.29 USD
6 months ago
May 01, 2024
Sell 108 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 25
4.32 USD
6 months ago
Apr 29, 2024
Sell 32.9 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 6680
4.92 USD
6 months ago
Apr 29, 2024
Sell 1.35 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 274
4.93 USD
6 months ago
Apr 29, 2024
Sell 494 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 100
4.94 USD
6 months ago
Apr 29, 2024
Sell 16.2 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 3231
5 USD
6 months ago
Apr 29, 2024
Sell 65.1 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 13
5.005 USD
6 months ago
Apr 29, 2024
Sell 2.25 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 448
5.025 USD
6 months ago
Apr 30, 2024
Sell 223 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 45
4.95 USD
6 months ago
Apr 30, 2024
Sell 225 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 45
5 USD
6 months ago
May 01, 2024
Sell 12.7 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 3100
4.1 USD
6 months ago
May 01, 2024
Sell 411 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 100
4.11 USD
6 months ago
May 01, 2024
Sell 7.21 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 1750
4.12 USD
6 months ago
May 01, 2024
Sell 1.57 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 380
4.13 USD
6 months ago
May 01, 2024
Sell 6.63 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 1600
4.145 USD
6 months ago
May 01, 2024
Sell 2.78 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 670
4.15 USD
6 months ago
May 01, 2024
Sell 1.67 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 400
4.18 USD
6 months ago
May 01, 2024
Sell 33.7 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 7923
4.25 USD
6 months ago
May 01, 2024
Sell 1.32 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 310
4.26 USD
6 months ago
May 01, 2024
Sell 1.35 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 317
4.265 USD
6 months ago
May 01, 2024
Sell 427 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 100
4.27 USD
6 months ago
May 01, 2024
Sell 855 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 200
4.275 USD
6 months ago
May 01, 2024
Sell 1.44 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 337
4.28 USD
6 months ago
May 01, 2024
Sell 857 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 200
4.285 USD
6 months ago
May 01, 2024
Sell 12.5 K USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 2903
4.29 USD
6 months ago
May 01, 2024
Sell 108 USD
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO
10 percent owner
- 25
4.32 USD
11 months ago
Dec 15, 2023
Bought 758 USD
WINDSOR JAMES BRIAN
President and COO
+ 225
3.37 USD
11 months ago
Nov 20, 2023
Bought 9.99 K USD
WINDSOR JAMES BRIAN
President and COO
+ 5076
1.9675 USD
3 years ago
Jan 08, 2021
Bought 9.9 M USD
Satter Muneer A
See Remarks
+ 9000000
1.1 USD
4 years ago
Jun 15, 2020
Bought 7.08 K USD
Ambros Reinhard J.
Director
+ 5800
1.22 USD
4 years ago
Jun 08, 2020
Bought 250 K USD
VON RICKENBACH JOSEF H
Director
+ 227272
1.1 USD
4 years ago
Jun 08, 2020
Bought 4.07 M USD
Satter Muneer A
director, 10 percent owner:
+ 3700000
1.1 USD
5 years ago
Nov 15, 2019
Bought 20 K USD
Bailey Jeffrey Allen
Director
+ 39142
0.51 USD
5 years ago
Nov 14, 2019
Bought 8.09 K USD
Bailey Jeffrey Allen
Director
+ 15858
0.51 USD
5 years ago
Nov 12, 2019
Bought 10.5 K USD
Bailey Jeffrey Allen
Director
+ 19894
0.53 USD
5 years ago
Sep 13, 2019
Bought 24.3 K USD
VON RICKENBACH JOSEF H
Director
+ 25000
0.9702 USD
5 years ago
Sep 12, 2019
Bought 86.2 K USD
VON RICKENBACH JOSEF H
Director
+ 88145
0.9785 USD
5 years ago
Sep 04, 2019
Bought 16.6 K USD
VON RICKENBACH JOSEF H
Director
+ 23225
0.714 USD
5 years ago
Sep 03, 2019
Bought 9.43 K USD
VON RICKENBACH JOSEF H
Director
+ 13466
0.7001 USD
5 years ago
Aug 30, 2019
Bought 11 K USD
VON RICKENBACH JOSEF H
Director
+ 15000
0.7312 USD
5 years ago
Aug 29, 2019
Bought 2.77 K USD
VON RICKENBACH JOSEF H
Director
+ 3600
0.7697 USD
5 years ago
Aug 16, 2019
Bought 44.5 K USD
Vukovic Vojo
SVP, Chief Medical Officer
+ 75000
0.5927 USD
5 years ago
Aug 13, 2019
Bought 29 K USD
Gregory Kathryn
SVP, Chief Business Officer
+ 45000
0.645 USD
5 years ago
Mar 29, 2019
Sell 197 K USD
Novartis Bioventures Ltd
10 percent owner
- 106540
1.85 USD
5 years ago
Apr 01, 2019
Sell 39.2 K USD
Novartis Bioventures Ltd
10 percent owner
- 20610
1.9 USD
5 years ago
Mar 13, 2019
Sell 281 K USD
Novartis Bioventures Ltd
10 percent owner
- 132738
2.12 USD
5 years ago
Mar 14, 2019
Sell 25.9 K USD
Novartis Bioventures Ltd
10 percent owner
- 13800
1.88 USD
5 years ago
Mar 15, 2019
Sell 84.1 K USD
Novartis Bioventures Ltd
10 percent owner
- 43800
1.92 USD
6 years ago
Aug 20, 2018
Sell 46.9 K USD
Novartis Bioventures Ltd
10 percent owner
- 20388
2.3 USD
6 years ago
Aug 16, 2018
Sell 18.5 K USD
Novartis Bioventures Ltd
10 percent owner
- 8808
2.1 USD
6 years ago
Aug 17, 2018
Sell 18.3 K USD
Novartis Bioventures Ltd
10 percent owner
- 8700
2.1 USD
6 years ago
Aug 14, 2018
Sell 7.46 K USD
Novartis Bioventures Ltd
10 percent owner
- 3300
2.26 USD
6 years ago
Aug 15, 2018
Sell 5.67 K USD
Novartis Bioventures Ltd
10 percent owner
- 2635
2.15 USD
6 years ago
Aug 10, 2018
Bought 24.5 K USD
LONGENECKER JOHN P PHD
President and CEO
+ 10000
2.45 USD
6 years ago
Aug 10, 2018
Sell 13.7 K USD
Novartis Bioventures Ltd
10 percent owner
- 5615
2.44 USD
6 years ago
Aug 13, 2018
Sell 3.78 K USD
Novartis Bioventures Ltd
10 percent owner
- 1600
2.36 USD
7 years ago
Jul 05, 2017
Bought 1 M USD
Kapnick Scott
director, 10 percent owner:
+ 66666
15 USD
6 years ago
Aug 08, 2018
Sell 2.78 K USD
Novartis Bioventures Ltd
10 percent owner
- 1000
2.78 USD
6 years ago
Aug 09, 2018
Sell 583 USD
Novartis Bioventures Ltd
10 percent owner
- 235
2.48 USD
6 years ago
Aug 06, 2018
Sell 8.88 K USD
Novartis Bioventures Ltd
10 percent owner
- 2942
3.02 USD
6 years ago
Aug 07, 2018
Sell 5.16 K USD
Novartis Bioventures Ltd
10 percent owner
- 1739
2.97 USD
6 years ago
Aug 02, 2018
Sell 15.7 K USD
Novartis Bioventures Ltd
10 percent owner
- 4702
3.33 USD
6 years ago
Jul 31, 2018
Sell 13.8 K USD
Novartis Bioventures Ltd
10 percent owner
- 4500
3.07 USD
6 years ago
Aug 01, 2018
Sell 26.3 K USD
Novartis Bioventures Ltd
10 percent owner
- 8181
3.22 USD
6 years ago
Jul 27, 2018
Sell 21.8 K USD
Novartis Bioventures Ltd
10 percent owner
- 6458
3.38 USD
6 years ago
Jul 30, 2018
Sell 6.54 K USD
Novartis Bioventures Ltd
10 percent owner
- 2000
3.27 USD
6 years ago
Jul 25, 2018
Sell 47.8 K USD
Novartis Bioventures Ltd
10 percent owner
- 12460
3.84 USD
6 years ago
Jul 26, 2018
Sell 28.8 K USD
Novartis Bioventures Ltd
10 percent owner
- 7937
3.63 USD
6 years ago
Jul 23, 2018
Sell 130 K USD
Novartis Bioventures Ltd
10 percent owner
- 30600
4.25 USD
6 years ago
Jul 24, 2018
Sell 2.88 K USD
Novartis Bioventures Ltd
10 percent owner
- 700
4.11 USD
6 years ago
Jul 16, 2018
Sell 1.54 K USD
Novartis Bioventures Ltd
10 percent owner
- 300
5.15 USD
6 years ago
Jul 17, 2018
Sell 58.9 K USD
Novartis Bioventures Ltd
10 percent owner
- 12500
4.71 USD
6 years ago
Jun 22, 2018
Sell 567 K USD
APPLE TREE PARTNERS II LP
10 percent owner
- 94816
5.9773 USD
6 years ago
Jun 25, 2018
Sell 5.35 K USD
APPLE TREE PARTNERS II LP
10 percent owner
- 913
5.8631 USD
6 years ago
Jun 26, 2018
Sell 57.4 K USD
APPLE TREE PARTNERS II LP
10 percent owner
- 10528
5.4545 USD
6 years ago
Jun 20, 2018
Sell 27.6 K USD
APPLE TREE PARTNERS II LP
10 percent owner
- 5200
5.3007 USD
6 years ago
Jun 21, 2018
Sell 7.67 K USD
APPLE TREE PARTNERS II LP
10 percent owner
- 1447
5.3 USD
6 years ago
Jun 15, 2018
Sell 42.3 K USD
APPLE TREE PARTNERS II LP
10 percent owner
- 7961
5.3191 USD
6 years ago
Jun 18, 2018
Sell 7.66 K USD
APPLE TREE PARTNERS II LP
10 percent owner
- 1432
5.35 USD
6 years ago
Jun 19, 2018
Sell 737 USD
APPLE TREE PARTNERS II LP
10 percent owner
- 139
5.3 USD
6 years ago
Jun 12, 2018
Sell 58.6 K USD
APPLE TREE PARTNERS II LP
10 percent owner
- 10843
5.4005 USD
6 years ago
Jun 08, 2018
Bought 16.2 K USD
Dougherty Donald
SVP & Chief Financial Officer
+ 3000
5.4 USD
6 years ago
Jun 07, 2018
Sell 110 USD
APPLE TREE PARTNERS II LP
10 percent owner
- 20
5.475 USD
6 years ago
Jun 08, 2018
Sell 52 K USD
APPLE TREE PARTNERS II LP
10 percent owner
- 9617
5.4032 USD
6 years ago
Jun 11, 2018
Sell 100 K USD
APPLE TREE PARTNERS II LP
10 percent owner
- 18525
5.4112 USD
6 years ago
Jun 06, 2018
Bought 5.61 K USD
Aivado Manuel
See Remarks
+ 1000
5.61 USD
6 years ago
Jun 01, 2018
Bought 10.5 K USD
Dougherty Donald
SVP & Chief Financial Officer
+ 2000
5.24 USD
6 years ago
Apr 17, 2018
Sell 21.9 K USD
APPLE TREE PARTNERS II LP
10 percent owner
- 3105
7.05 USD
6 years ago
Apr 19, 2018
Sell 660 K USD
APPLE TREE PARTNERS II LP
10 percent owner
- 104799
6.293 USD
6 years ago
Jan 09, 2018
Sell 1.47 M USD
APPLE TREE PARTNERS II LP
10 percent owner
- 150000
9.8029 USD
7 years ago
Jul 05, 2017
Bought 3.75 M USD
Shanafelt Armen
Director
+ 250000
15 USD
7 years ago
Jul 05, 2017
Bought 3.75 M USD
LV Management Group, LLC
+ 250000
15 USD
7 years ago
Jul 05, 2017
Bought 374 K USD
AJU IB Investment Co., Ltd.
10 percent owner
+ 24929
15 USD
7 years ago
Jul 05, 2017
Bought 4.1 M USD
Gallagher Brian M. Jr.
Director
+ 273333
15 USD
7 years ago
Jul 05, 2017
Bought 2.85 M USD
Sigma Emerging Markets Ltd.
10 percent owner
+ 190000
15 USD
7 years ago
Jul 05, 2017
Bought 900 K USD
EXCEL MEDICAL FUND LP
10 percent owner
+ 60000
15 USD
7 years ago
Jul 05, 2017
Bought 500 K USD
Satter Muneer A
10 percent owner
+ 33333
15 USD
7 years ago
Jul 05, 2017
Bought 3 M USD
KCK LTD.
10 percent owner
+ 200000
15 USD
7 years ago
Jul 05, 2017
Bought 1.79 M USD
ROCHE HOLDING LTD
10 percent owner
+ 119400
15 USD
7 years ago
Jul 05, 2017
Bought 2.7 M USD
CVF, LLC
10 percent owner
+ 180000
15 USD
7 years ago
Jul 05, 2017
Bought 1 M USD
Kapnick Scott
director, 10 percent owner:
+ 66666
15 USD
7 years ago
Jul 05, 2017
Bought 2.39 M USD
Kapnick Scott
director, 10 percent owner:
+ 159307
15 USD
7 years ago
Jul 05, 2017
Bought 4 M USD
Ambros Reinhard J.
Director
+ 266667
15 USD
7 years ago
Jul 05, 2017
Bought 4 M USD
Novartis Bioventures Ltd
10 percent owner
+ 266667
15 USD
12 years ago
Jan 03, 2012
Bought 2 M USD
GELMAN GARY
Chairman, President & CEO
+ 1000000
2 USD
7. News
Aileron Therapeutics Reports Third Quarter 2024 Financial Results and Recent Business Highlights Announced promising safety and positive biomarker data from Cohort 2 (5mg BID) of the Phase 1b clinical trial of LTI-03 in idiopathic pulmonary fibrosis (IPF) patients demonstrating dose dependent effects in five biomarkers evaluated compared to low dose LTI-03 Data from Cohort 2 of the Phase 1b clinical trial confirms results from Cohort 1, with four biomarkers achieving statistical significance in the combined Cohort 1 and Cohort 2 data set Planning is underway for a Phase 2 clinical trial AUSTIN, Texas , Nov. 14, 2024 /PRNewswire/ -- Aileron Therapeutics, Inc. ("Aileron") (NASDAQ: ALRN), a biopharmaceutical company advancing a novel pipeline of first-in-class medicines to address significant unmet medical needs in orphan pulmonary and fibrosis indications, today reported financial results for the third quarter ended September 30, 2024, and provided a business update. "This past quarter has been one of significant progress for Aileron, as evidenced by our recent announcement of positive data from Cohort 2 of our Phase 1b clinical trial evaluating a higher dose of LTI-03 (5 mg BID) in patients with IPF, in which high dose LTI-03 demonstrated dose dependent effects in five biomarkers," said Brian Windsor, Ph.D. prnewswire.com - 2 days ago
Aileron Therapeutics Announces Positive Topline Data from Cohort 2 of the Phase 1b Clinical Trial of LTI-03 in Idiopathic Pulmonary Fibrosis (IPF) High-dose LTI-03 (5 mg BID), a Caveolin-1 related peptide, reduced expression of multiple profibrotic proteins in both pathological basal-like cells and fibroblasts and decreased the expression of a biomarker indicative of epithelial health and lung function decline, suggesting potential therapeutic effect Positive trend observed in seven out of eight IPF biomarkers in Cohort 2, with four biomarkers statistically significant in the combined Cohort 1 and Cohort 2 data set, and dose dependent movement of five biomarkers compared to low dose LTI-03 indicative of active LTI-03 pharmacodynamics High-dose LTI-03 was well-tolerated, with no safety signals observed Planning is underway for a Phase 2 clinical trial Company to host conference call today at 8:30 am ET WALTHAM, Mass. , Nov. 13, 2024 /PRNewswire/ -- Aileron Therapeutics, Inc. ("Aileron") (NASDAQ: ALRN), a biopharmaceutical company advancing a novel pipeline of first-in-class medicines to address significant unmet medical needs in orphan pulmonary and fibrosis indications, today announced positive topline data from Cohort 2 of its Phase 1b clinical trial evaluating the safety and tolerability of inhaled LTI-03 in patients diagnosed with idiopathic pulmonary fibrosis (IPF). prnewswire.com - 3 days ago
Aileron Therapeutics and Advancium Health Network Announce an Exclusive Option Agreement for the Acquisition of ALRN-6924 for Retinoblastoma Agreement marks first of its kind for Advancium, a public charity launched by Deerfield Management and the Deerfield Foundation Advancium will evaluate ALRN-6924 as a potential therapy for retinoblastoma, a rare but devastating pediatric cancer of the eye AUSTIN, Texas and NEW YORK , Oct. 31, 2024 /PRNewswire/ -- Aileron Therapeutics, Inc. ("Aileron") (NASDAQ: ALRN), a biopharmaceutical company advancing a novel pipeline of first-in-class medicines to address significant unmet medical needs in orphan pulmonary and fibrosis indications, and Advancium Health Network ("Advancium"), a public charity founded by Deerfield Management and the Deerfield Foundation to meet the needs of underserved patient populations, today announced entry into an exclusive option agreement for the acquisition of ALRN-6924, a clinical-stage oncology agent developed by Aileron prior to its 2023 merger with Lung Therapeutics, Inc. During the option period, Advancium intends to evaluate ALRN-6924 as a potential therapy for retinoblastoma (RB), a rare but devastating cancer of the eye, with around 300 cases diagnosed in the United States and 9,000 cases worldwide each year, nearly all in children [1]. With early intervention the disease is rarely fatal; however, non-selective chemotherapy with its attendant side effects remains the usual treatment strategy, and removal of the affected eye(s) is a frequent outcome. prnewswire.com - 2 weeks ago
Aileron Therapeutics to Present Previously Announced Data from the Phase 1b Clinical Trial Evaluating Low-Dose LTI-03 in Idiopathic Pulmonary Fibrosis (IPF) at the 22nd International Colloquium on Lung and Airway Fibrosis First scientific presentation of previously announced data from Cohort 1 of the ongoing Phase 1b clinical trial evaluating low-dose LTI-03 (2.5 mg BID) in IPF, affirms positive trends in seven of the eight biomarkers evaluated, suggesting potential therapeutic effect Recently completed enrollment of Cohort 2 evaluating high-dose LTI-03 (5 mg BID) in mid-September; topline data expected in the near-term AUSTIN, Texas , Oct. 12, 2024 /PRNewswire/ -- Aileron Therapeutics, Inc. ("Aileron") (NASDAQ: ALRN), a biopharmaceutical company advancing a novel pipeline of first-in-class medicines to address significant unmet medical needs in orphan pulmonary and fibrosis indications, today announced the presentation of two abstracts detailing LTI-03's pre-clinical and Phase 1b (NCT05954988) results in Idiopathic Pulmonary Fibrosis (IPF) at the 22nd International Colloquium on Lung and Airway Fibrosis (ICLAF). The Company previously  announced positive data  from Cohort 1 of the ongoing Phase 1b clinical trial evaluating low-dose LTI-03 (2.5 mg BID) in patients with IPF. prnewswire.com - 1 month ago
Aileron Therapeutics Completes Enrollment in Cohort 2 of the Ongoing Phase 1b Clinical Trial Evaluating LTI-03 in Idiopathic Pulmonary Fibrosis (IPF) Cohort 2 will evaluate high-dose LTI-03 (5 mg BID) Previously announced Cohort 1 data demonstrated positive trends in seven of the eight biomarkers evaluated, suggesting a potential therapeutic effect AUSTIN, Texas , Sept. 23, 2024 /PRNewswire/ -- Aileron Therapeutics, Inc. ("Aileron") (NASDAQ: ALRN), a biopharmaceutical company advancing a novel pipeline of first-in-class medicines to address significant unmet medical needs in orphan pulmonary and fibrosis indications, today announced the completion of enrollment in Cohort 2 of the ongoing Phase 1b clinical trial of LTI-03 in IPF patients. prnewswire.com - 1 month ago
Aileron Therapeutics to Present at the 8th Annual IPF Summit AUSTIN, Texas , Aug. 19, 2024 /PRNewswire/ -- Aileron Therapeutics, Inc. ("Aileron") (NASDAQ: ALRN), a biopharmaceutical company advancing a novel pipeline of first-in-class medicines to address significant unmet medical needs in orphan pulmonary and fibrosis indications, today announced that Brian Windsor, Ph.D., President and Chief Executive Officer of Aileron, will present at the 8th Annual IPF Summit taking place August 20-22, 2024 in Boston, MA. prnewswire.com - 2 months ago
Aileron Therapeutics Reports Second Quarter 2024 Financial Results and Business Highlights Announced positive data from Cohort 1 of the ongoing Phase 1b clinical trial of LTI-03 evaluating low dose LTI-03 (2.5 mg BID) in idiopathic pulmonary fibrosis ("IPF") patients, with positive trends observed in seven of the eight biomarkers evaluated Topline results from Cohort 2 evaluating high-dose LTI-03 (5 mg BID) expected in the third quarter of 2024 AUSTIN, Texas , Aug. 14, 2024 /PRNewswire/ -- Aileron Therapeutics, Inc. ("Aileron" or the "Company") (NASDAQ: ALRN), a biopharmaceutical company advancing a pipeline of potential first-in-class medicines to address significant unmet medical needs in orphan pulmonary and fibrosis indications, today reported financial results for the second quarter ended June 30, 2024, and provided a business update. "Throughout the first half of the year, we focused on strengthening our balance sheet and advancing the development of inhaled LTI-03 in IPF," said Brian Windsor, Ph.D. prnewswire.com - 3 months ago
Aileron Therapeutics to Present at the Canaccord Genuity 44th Annual Growth Conference AUSTIN, Texas , July 30, 2024 /PRNewswire/ -- Aileron Therapeutics, Inc. ("Aileron") (NASDAQ: ALRN), a biopharmaceutical company advancing a novel pipeline of first-in-class medicines to address significant unmet medical needs in orphan pulmonary and fibrosis indications, today announced that Brian Windsor, Ph.D., President and Chief Executive Officer, will present at the Canaccord Genuity 44th Annual Growth Conference on Tuesday, August 13, 2024 at 4:00 p.m. prnewswire.com - 3 months ago
Aileron Therapeutics to be Included in the Russell Microcap® Index AUSTIN, Texas , July 1, 2024 /PRNewswire/ -- Aileron Therapeutics, Inc. ("Aileron" or the "Company") (NASDAQ: ALRN), a biopharmaceutical company advancing a novel pipeline of first-in-class medicines to address significant unmet medical needs in orphan pulmonary and fibrosis indications, today announced that the Company is set to join the Russell Microcap® Index at the conclusion of the 2024 Russell U.S. Indexes annual reconstitution, effective at the open of US equity markets on Monday, July 1, 2024. The annual Russell U.S. Indexes reconstitution captures the 4,000 largest U.S. stocks as of Tuesday, April 30th, ranking them by total market capitalization. prnewswire.com - 4 months ago
Aileron Therapeutics Reports First Quarter 2024 Financial Results and Business Highlights Announced positive data from Cohort 1 of the Phase 1b clinical trial of LTI-03 in idiopathic pulmonary fibrosis (IPF) patients with positive trends observed in seven of the eight biomarkers evaluated globenewswire.com - 6 months ago
Down -36.29% in 4 Weeks, Here's Why Aileron Therapeutics (ALRN) Looks Ripe for a Turnaround The heavy selling pressure might have exhausted for Aileron Therapeutics (ALRN) as it is technically in oversold territory now. In addition to this technical measure, strong agreement among Wall Street analysts in revising earnings estimates higher indicates that the stock is ripe for a trend reversal. zacks.com - 6 months ago
Aileron Therapeutics to Present at Two Upcoming Investor Conferences AUSTIN, Texas, May 06, 2024 (GLOBE NEWSWIRE) -- Aileron Therapeutics, Inc. (“Aileron”) (NASDAQ: ALRN), a biopharmaceutical company advancing a novel pipeline of first-in-class medicines to address significant unmet medical needs in orphan pulmonary and fibrosis indications, today announced that Brian Windsor, Ph.D., President and Chief Executive Officer, will present at two upcoming investor conferences: globenewswire.com - 6 months ago
8. Profile Summary

Aileron Therapeutics, Inc. ALRN

image
COUNTRY US
INDUSTRY Biotechnology
MARKET CAP $ 62.2 M
Dividend Yield 0.00%
Description Aileron Therapeutics, Inc. operates as a clinical stage chemoprotection oncology company in the United States. The company is developing ALRN-6924, which is in Phase 1 trial for solid tumor and lymphoma; Phase 2a clinical trial to treat peripheral T-cell lymphoma; Phase I clinical trial for the treatment of acute myeloid leukemia (AML) and advanced myelodysplastic syndrome (MDS); Phase 1b trial to test the combination of ALRN-6924 and cytarabine, or Ara-C, in patients with MDS; and a Phase 2a combination trial of ALRN-6924 and palbociclib in patients with tumors harboring MDM2 amplifications co-amplifications, as well as for patients with p53-mutated small cell lung cancer that has completed Phase 1b clinical trial. It has a license agreement with Dana-Farber Cancer Institute and Harvard College; and Umicore Precious Metals Chemistry USA, LLC. The company was formerly known as Renegade Therapeutics, Inc. and changed its name to Aileron Therapeutics, Inc. in February 2007. Aileron Therapeutics, Inc. was incorporated in 2001 and is based in Boston, Massachusetts.
Contact 285 Summer Street, Boston, MA, 02210 https://www.aileronrx.com
IPO Date June 29, 2017
Employees 15
Officers Dr. James Brian Windsor Ph.D. Chief Executive Officer, President & Director Mr. Timothy M. Cunningham CPA, M.B.A. Interim Chief Financial Officer & Principal Accounting Officer